The general principle of the recommendations is to add a second drug that is not cross-resistant with the first (eg, adding a nucleotide drug such as adefovir or tenofovir when resistance to a nucleoside agent such as lamivudine, telbivudine, or entecavir is detected. The opposite concept applies to the patient with adefovir resistance (ie, add a nucleoside agent).
Because Truvada is a combo of emtricitabine and tenofovir, I guess you are right that Entecavir would be the rescue drug, but am not sure.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.