should i start treatment

[longlife34]

I have been living with Hep B since birth, I am now 34 years of age.

I have been getting ultrasound and HBV DNA test every 6 months along with liver panel tests.  My recent test are

Normal ultrasound
HbeAg -negative
HbeAb-positive
Hbv Dna 650 copies
Alt 12
Ast 13
my doctor states I am inactive at the moment and do not need treatment at the moment.  I wanted to get your opinion on this.  Any feed back would be welcomed.   I am constantly worried if I should start treatment or not.  thanks for you helpt in advance

[bkhanal]

hello..i had rested hep b in 22years of age. it was +ve..i didnt get any test of liver..now im 28years running..lots of symtoms are similer of hep b like loss of appitire, abdominal pain, muscels pain..im now verry tens..no i have given blood for dna,lft and hbeag..after 10days ill get report..so please tell me any body what % chance of liver damage..bot liver ultrasound is normal..so pleasee...!

[stef2011]

just follow the community regularly to know first

and precore I always read that this HBV E negative leads to a poor prognosis?
this is the main form of hbv, wild type is the rare form now, eradication of hbv is only correlated to hbsag quantity with current drugs.

the new drugs like replicor or gcmaf will probably clear hbv fast whatever the phase

[longlife34]

Hello there,

do you think that new drugs are on the horizon or will they take a long time to be ready? What new drugs are coming

Also, is it possble for me to stay inactive for a long time because I am genotype d and precore I always read that this HBV E negative leads to a poor prognosis?

[stef2011]

you dont need any treatment but find a place to make hbsag quantification by architect in iu/ml, if you find hbsag lower than 1500iu/ml which is very probable on inactive patients, you can clear hbv by interferon or alinia (nitazoxanide) or combo of both

it worths doing this therapy only if hbsag is 1000-1500iu/ml if higher you better wait for new drugs which can cure hbv which will be available soon, now all drugs are ineffective on hbv cure