stef.. need your help

[pcdmd]

In Nov-13, I was detected for HBV.
HBSAG (88 IU/ML), HBEAG -ve, HBVDNA 2500 IU/ML, ALT-28

In Feb-14, HBVDNA was 600 IU/ML, ALT 22

In June-14, HBVDNA dropped to 65 IU/ML, HBSAG 40 IU/ML, ALT 21

I have two questions:

1. Is my virus sero-converting? (I read some research that <200 IU/ML.. If HBSAG drops sequentially, the chances are high that virus is seroconverting.)
2. If not, Shall I take some medications to assist the process??

[sorte]

Is it common that his ALT stays normal when his immune system cleans up hbsag and hbv dna? I thought that in such case there will be always some ALT increase less or more ?
Does HBeAg- has some influence or it doesn't matter in that case ?

[stef2011]

did you correct vitd25oh to 100ng/ml?and atthe same time checked intact pth when vitd25oh is at 100ng/ml?

that s the only thing that can help speed up hbsag loss

if hbsag has reached 20iu/ml in such a short time you ll clear in the following 5 to 10years

please let us know how hbsag changes after vitd25oh becomes 100ng/ml stable for 6-8months-to do this you need vit d3 10.000iu daily, drink at least 2L of water daily

[pcdmd]

hi Stef... sorry to bother you again. Here is my case:

HBV Detected in Nov13. HBEAG -ve
HBVDNA= 2200 IU/ML (nov-13), 600 (Jan-14), 80 (May-14), Undetected (Dec-14), Undetected (April-15)
HBSAG= 80 iu/ml (nov-13), 40 iu/ml (June-14), 32 iu/ml (Sep-14), 25 iu/ml (Dec-14), 20 (Apr-15)
ALT Last 1.5 year data, every quarter: 30, 21, 20, 20, 25

Any recommedation for me??

[heprob]

Thank you..

[stef2011]

check fibroscan, vitd25oh and intact parathormone

[heprob]

from philippines
hbv

i need somebody to help in my case.. these are my symptoms ,every after taking a bath i fel intense itching,sometimes at night or day i had itch in my finger neck and toe,i got blood on my saliva sometimes freshblood when i woke up or sometimes i spit blood with my saliva or when at work when i goto cr ,i have abdominal pain im right ribs, dry mouth, sleepless,muscle pain ,wasting , and athritical pain.....and im afraid of having liver cirrhosis because of this symptoms, corrrect me if im wrong with it.. as ive heard and observe with this forum of having the same illness.. i dont know what im going to do because the doctor's ddnt give some med of this ,as what they have seen on my lab result  which is normal status ,

hbsAg w/titer (cmia)  --  4111.63      date  : 10/20/14
hbsAg w/titer (cmia)  -- 3988.29       date  :  1/02/15
my hvdna                    23 iu/ml 134 copies/ml ..  date  :  1/28/15

by 10/20-2014

protohrombin time
pt               12.80 sec 10-14               sgpt 25,sgot 24
  %activity      86.5                               alkaline phosphatase 97
   INR             1.06                               albumin    4.77,globulin   2.40
   control 12.00                                    direct biliburin   0.35
    control activity  109.5                       inderict biliburin 0.57
                    
1/16-2015
pt               11.80  sec 10-14               sgpt 39,
   INR           0.98                                 albumin    4.9,
   control 11.80                                    direct biliburin   0.36
    control activity  70.9                         inderict biliburin 0.53

by 1/28/15
my hvdna             23 iu/ml 134 copies/ml ..  date  :  1/28/15
my sgpt                 29

but im getting worst time after time of what i feel right now , and the doctor hepatology
ddnt give me any med ,even i explain the sypmptoms which is geeting worse..she advice me to go ct scan to prove what was really the cause of
my symptoms which is really bothering me..
                            
earlier at first i thought because of my gallstone 8 mm @ my ultrasound 5/10/2013, then it happens the pain i gone because i used to flush it as ive heard others do, then go back drinks some beer .then,  the mild pain back  then ultra sound again 10/25/13 the result reduced into 4 mm,which i wonder.. ultra sound again 1/02/15 to the other lab, and they found out it turns to gallbladder polyps ... the rest is normal the liver the spleen...

i need some of advice ,who experience like this
i apologize of my english the way of delivering my grammar...


thank you ..

[mike9111]

I beleive doctors could tell if it was acute or chronic from your hbv blood test. You have a very good chance to eliminate it by yourself however pegint my speed up the process

[pcdmd]

In Nov-13, I was detected for HBV.

HBSAG (88 IU/ML), HBEAG -ve, HBVDNA 2500 IU/ML, ALT-28

In Feb-14, HBVDNA was 600 IU/ML, ALT 22

In June-14, HBVDNA dropped to 65 IU/ML, HBSAG 40 IU/ML, ALT 21

In Sept-14, HBSAG 32 IU/ML, ALT 21

In Dec-14, HBVDNA Undetected (<20), HBSAG 25 IU/ML, ALT 20

Have not taken any medicine. My question is:

Given that both HBVDNA and HBSAG have fallen steadily, is it safe to assume:

1. That my infection isnt there since birth and it has happened recently?
2. That my body is fighting with HBV virus still, therefore, it may eliminate the virus in next couple of months?

[sam_mir]

Hi,
I have recently been diagionased with HEP B positive after have the symptoms Like jaundice and vomitting. I have asked to do some more tests like PCR and antibody tests. I want to know that if I have an Acute or a chronic since the symptoms date 3-4 weeks back. Please advise and is there and dietary precausition.
regards,
Sam

[stef2011]

yes this is one of the many many studies about hbsag guided response hbv combo therapy

[pcdmd]

Is the following study a research backdrop of your recommendation?


http://www.ncbi.nlm.nih.gov/pubmed/25009392

[pcdmd]

Ok. Thanks. Could you also help me with some research work which concludes that medicine for hbsag<200 help eradicate this virus?

[stef2011]

buy peginterferon yourself, add vitamin d3 20.000iu daily and have doctor monitor response to peginterferon

also check calcium in urine monthly and avoid all dairies products, drink 2.5l of water daily while on vit d3 20.000iu

[pcdmd]

Hi Stef, could you please sight some study (reserach work) which builds a case of treating patients based on hbsag marker? Frustrating it is that docs in india refuse to give medicines for patients whose hbvdna<2000 iu/ml. You have been vociferously recommending treatment for people like us whose hbsag<200 iu/ml.

Just for ref. my hbvdna is 65iu/ml, hbsag is 34iu/ml. Normal ALT.

[stef2011]

as your doctor for natural compounds first or paracetamol and if they dont work go for what he says

[stef2011]

first of all you need to find the reason of headache and then try the light drugs for that like paracetamol in correct doses (paracetamol overdose is very toxic  to the liver as most drugs are)

[pcdmd]

hi.. I have had headache for past one month. My GP has recommended flunarizine. Is it okei to take it for hbv-ers??

[stef2011]

milk is not ok, it is full of ormones, antibiotics and crap food given to the animals.calcium from milk is also not beneficial to the bones and kinetics of calcium/vit d

use oat milk with no calcium added

[stef2011]

yes you are right

vitd is deficient as all hbver and pth shows your vit d receptors are not blocked, so you will benefit from a level of 90-100ng/ml

it is best to take daily vit d3 instead of weekly/monthly, all studies found benefit from daily because the levels stay stable (weekly or monthly makes flares of vit d when you take it and then go down).10.000iu daily would be best

[pcdmd]

Thanks Stef. Two points:

1. My HBSAG reports reads as follows:

Immunoassay
HBSAG Screening (Serum, CMIA)   Reactive (39.88) IU/ML

Am I right in interpreting that my HBSAG is 39.88 IU/ML? The same number was 80, 6 months ago.

2. My Vit d3 is 29 and PTH is 22.5. My doc suggested cholecaliferol granules 60000 iu/ml every week for 4 weeks... with milk... he is right???

[stef2011]

if not advanced you can manage diabetes and lower or discontinue metformin

http://articles.mercola.com/sites/articles/archive/2010/09/02/diabetes-most-of-what-youve-been-told-may-be-wrong.aspx

getting vitd25oh to 90-100ng/ml is the first and most important step together with getting pth to lower range of normal 11-20pg/ml
discontinue everything from dairies and use oat milk with no calcium added to it, drink 2l of water daily
also fish oil can help a lot, dha+epa must be at least 2,5g per day and fish oil certified no/very low mercury or pcb (few brands like this, nordic naturals for example)

recheck everything in 6months of diet and vit d, of course this is very beneficial to liver and general health too

[pcdmd]

Yes. It's type 2. I am on metformin. 1000mg a day.

Thanks Stef for all the assistance..and keep up the good work u are doing. It's altruism indeed.

[stef2011]

is it diabetes 2?are you on vit d3 and special diet or drugs?

that will make your risk of liver cancer extremely high, diabetes is the worst thing for liver and liver cancer unless you reverse that naturally without drugs

although diabetes alone take hcc risk to more than 30% it is best to get rid of hbv and not add other risk

[stef2011]

My docs sound confident in not recommending anything as my virus is silent!

my god this type of words is more from witches than doctors, anyway while it is so called silent you can cure hbv once and for all and it worths the sides effects of peginterferon....if the virus is replicating and hbsag higher peginterferon will not cure anything more than 7% of patients, this is criminal.i think they are just ignorant  and they dont know how to cure hbv, look for the most expert liver specialist and when you ask for appointment require "cure of hbv by personalized peginterferon treatment according to hbsag levels" if they are not able to do this dont even waste time and money to take appointment

of course there can be sides effects to peginterferon, even severe, but this is the only way we are getting cured, if you feel you can t tollerate them you just stop peginterferon and keep hbv