actually the latest studies like this have found rare liver damage in persistently normal alt below 30, the alt level to exclude any related liver death/liver damage is below 20
it is a pity they didn t check those biopses with the bcp/precore mutants if there is correlation with liver damage
monitoring with fibroscan yearly can exclude easily liver damge in hbvdna detactable
“Significant liver disease is rare in patients with chronic HBV and persistently normal ALT,” the researchers concluded.