wonderfull presentation of easl 2011 conference results
most interesting findings:
sustained immune response only on those with:
cccdna equal or less than 5 copies/cell this is probably about hbsag 500iu/ml or less
exclusion of cirrhosis by fibroscan (most useful everyday tool to monitor liver damage/fibrosis)
>8kpa significant lesions, therapy necessary
hbsag level to predic seroclearance of hbv
hbsag<200 iu/ml prediction of hbv clearance by 1-5years see table on file
hbsag<100iu/ml prediction of hbv clearance by 1-5years see table on file
of course the lower hbsag the most probablility of hbv eradication
risk of liver cancer, at hbvdna undetactable 1.5% at 18years, very close to 0% at about 8 years (they dont say but this is probably without cirrhosis)
tables of hbsag decline in interferon+ antivirals combo etv or tnf or adv (on report interferon+tnf+etv) and eradication of hbv, see tables in file
tables about rep 9 ac replicor (probably a bomb therapy if combined with etv or tnf)
LB80380 for lam resistance mutants
gs9620 from gilead - the results of this on animals look too generic to say, i'd wait to see human trials because it looks like there is a relapse after end of therapy they used compound for too short time to have a real meaning
Copyright 1994-2016 MedHelp International. All rights reserved.
MedHelp is a division of Aptus Health.
This site complies with the HONcode standard for trustworthy health information.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.