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worried about hepatitis-b non-reactive

what is hepetitis-b non-reactive means?isn't danger of having that?  is there any solution or medicine for hepatitis-b non-reactive
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Avatar universal
what does hepatitis B Surface Antibody Non reactive, 0.0 mlU/mL means?
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Avatar universal
What does it mean if a test result says Hepatitis B reactive? Is there a treatment for it, thats if it is a problem?
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Avatar universal
This is Ali form Kabul, having Hepatitis B Non Reactive, So, please would you instruct me what medicine should i take and what steps are necessary for me to take it or pass it.
Please waiting for your answers and instructions
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Avatar universal
I got my hepB vaccine a year ago. I had to get checked out to see if I in fact am immunized. I went to the doc, to check whether the surface Ab is present, the nurse told me a week later it is present. I got a copy of the report it is from quest. it looks so weird  as follows:
Test name                 In Range                                Out of Range                         Reference Range

Hepatitis B surface                                                   REACTIVE                          NON-REACTIVE
Antibody QL

thats all it says...what does it mean? why is in range left blank?
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92903 tn?1309904711
Best wishes on your 30 day. I'll be thinking of you. Be sure to post the results, would ya?

Ditto your comments on influencing treatment decisions by being informed. My doc is knowledgeable, trained, compassionate, and eerything else you could ask. But no way he could chase down all the minutia that applies to my case. Also, while no one gets special treatment, I have to think you serve yourself well by demonstrating a commitment to your own treatment.
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Avatar universal
Bill said: He ended up giving me a stack of signed blank lab orders and told me to go ahead and spec the remaining VL assays).
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LOL. Sounds like what happend with my doc. Either shows your doc trusts you, or has just given up. In either case, you've won!!!

Something to think about. I like starting with the PCR real time quant, but you can have it reflexed to the qual TMA, meaning they will imed run the TMA if the quant is <50. Or, you can just be optimistic and order them separate which means they'll be run at the same time regardless of the PCR results. This is different from Heptimax where the same real time PCR quant is reflexed to a quantitative TMA as opposed to a qualitative TMA. I've been staying with Heptimax for consistency but to do it all over again, I'd either go with PCR reflexed to qual TMA or as Goofy doc does which is Bdna quant and qual TMA (those can be reflexed as well with Quest).

Hey...but more important than all this...ALL THE BEST LUCK... whichever test you check off.

-- Jim

PS I'll check out that study later
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87972 tn?1322661239
Gents--
Thanks for your time and thoughts on this subject. As I mentioned in an earlier post, I was fortunate enough to hear a research RN with CPMC
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Avatar universal
Through  Quest, you can also order the bDNA quant to reflex to the TMA. In other words, they'll only run the TMA if the bDNA is negative. This can potentially save money but would probably take a day or two longer for results since both tests would not be run concurrently as they would be if ordered separate. Of course, if it turns out your bDNA negative and TMA positive, you'll only know that your viral load is somewhere between 10 IU/ml and 615 IU/ml. To get exact load, I guess you'd then have to run a third test -- their real time PCR. With Heptimax, you get continuous numbers from 5 IU/ml to way on up. Therefore different tests probably make more sense at different stages of treatment or post treatment depending on what type of info you want.
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92903 tn?1309904711
I lost your post on Gish, specificity, etc. Anyway, consistent with the comments you heard, I can tell you the pre-printed form at CPMC includes bDNA quant, PCR quant, and TMA qual. No Heptimax.

From what we've learned here lately, my guess is that bDNA is most accurate for measuring changes in VL, TMA for a boolean evaluation, and PCR for measuring lower levels of load. Also, PCR seems to be turned around more quickly when that counts.

I haven't a clue as to how the ultra-low (<2) PCRs fit into the equation.  

Hope you are well.
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92903 tn?1309904711
In answer to your inquiry:

bDNA comes back as < 615.
TMA comes back as undetected.
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Avatar universal
"hepatitis b non-reactive" can mean several different things.  it all depends on what kind of test you took.

if you took a HBsAg test and you came up non-reactive, then you do not have hep b.

if you took a HBsAB test and you came up non-reactive, then that means you do not have the anti-body, but it doesn't say whether or not you have Hep B.

there are several other tests that are routinely given for hep b, but the two above are the most common.  find out what test was given to you, and if your doctor can't interpret them, we'll help you out.

leeac
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Avatar universal
I didn't mean "range" on the TMA, I meant detection limit.
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Avatar universal
Thanks for the Quest test info.

Just to be clear, does your quantitative have range of 615 IU/ml -- 7.57 IU/ml and your TMA  a range of 9-10 IU/ml?

BTW it appears that the BDNA Quant by Bayer is the only FDA approved test for hepatitis C and that may be why so many doctors use it.  Another interesting fact, is that it's not a PCR but a branch DNA , i.e BDNA.
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92903 tn?1309904711
Thanks. I'm outta here. Time to enjoy the sun and a riba free day.
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Avatar universal
Goofy said:Well, you know I always like learning from those who have traveled before me. In that vein, I'll follow your advise. Thanks for the heads up. I appreciate the tip and hope this isn't a hard nut to crack.
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No problem, always glad to share my ups and downs. BTW check out post in "Anyone Got Pain" thread before it gets buried.

-- Jim
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92903 tn?1309904711
Well, you know I always like learning from those who have traveled before me. In that vein, I'll follow your advise. Thanks for the heads up. I appreciate the tip and hope this isn't a hard nut to crack.
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Avatar universal
Goof said: And I need to call for another booster since I'm still non-reactive
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I'd try Viagra before calling another escort service.
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Avatar universal
Oh man I forgot to have my last booster for the hepa hepb shot - I'm so glad you said that about boosters Or I never would have remembered!  I'm only a week behind right now thank GOD.

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Avatar universal
Goofy said: t simpley means you've never been exposed to the irus
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In high school we were all warned to stay away from Irus. No doubt that is why ACS is non-reactive.
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92903 tn?1309904711
It simpley means you've never been exposed to the irus. That's good news, unless you've had a hep B vaccine, in which case this likely means the vaccine didn't work and you may need a booster.
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92903 tn?1309904711
.... and I need to call for another booster since I'm still non-reactive :(
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