lab values after incivek

Do lab values usually get better after stopping incivek.... Hbg @9.1.....  Stop inc the same day got labs.

[willbb]

If the Inci has had an effect on lowering the  HGB. levels should improve somewhat within 6 to 8 weeks of  stopping Inci. ,however INF. and Riba may still be causal of low HGB.  Have you reduced Riba or taking Procrit.?

Will

http://hepatitiscnewdrugs.blogspot.com/2012/01/boceprevir-and-telaprevir-for-hepatitis.html

Anaemia is a well-known RBV-related event which is exacerbated by the addition of TVR and BOC. The mechanism of anaemia with both DAA was not because of haemolysis but was thought to be the result of a bone-marrow suppressive effect. In clinical trials, triple therapy with TVR or BOC was associated with an increase in the incidence (approximately 20%) and severity of anaemia compared to PEG-IFN/RBV alone (Table 1). The frequency of anaemia, defined as haemoglobin levels below 10 g/dl, was about 50% for triple therapy with BOC and 40% with TVR. Haemoglobin values gradually improved after the end of TVR dosing at week 12 and were similar to those with PEG-IFN/RBV alone by week 20.

[crigger]

No I just pick up my labs yesterday. I have not heard from DR .the labs were drawn a week ago I guess I should call him and ask what the plan is. Hbg is getting low. I just hate the thought of adding something else.

[willbb]

Yes..with HGB of 9 .. calling the doctor and asking what the plan is would certainly be advised   :)

Sorry don't know your particulars however if you are UND. and well into tx. a slight dose reduction(as per protocol for anemia) as well as now being off the Inci.it may be enough to raise HGB,however procrit is also an option used by many doctors.It can take 3 to 6 weeks to have an effect though.
Best to get in touch with the doc and get things organized...
Good luck ...
Will