24 WK PCR-VL tripled

I guess I want you guys to tell me what I already know.
My VL was 67000 at 12 weeks and at 24, it is 189000.
Recap:  47yo F, 1a, no biopsy,initial load 6.8 mil

[Forseegood]

So sorry to hear of this, hope you get some good answers soon.

[nanniegea]

Sorry to hear that your levels are rising. Did the Doc say anything about what could be done about it or are you going to just continue on and see what the next test says? Whatever happens I will keep good thoughts that levels start to drop for you. Are you on inteferon and rivarin? Maybe you need to up the dose of one or the other? Please let us know how you make out.

[NYgirl]

Oh my God I am so sorry you must be feeling exactly like I would be.  There are no words except hang in there...time to figure out the next move!

Look at someone like Cuteus who refused to give up...and what she has now!

My prayers are with you.

[bobbyullc]

real sorry, that is a hugh disapointment. i think i would now get a biopsy to see how bad it is and if there is an option to await new drugs or try whatever is on the table now.
good luck, our prayers are with you.
bobby

[GoofyDad]

Awwww Maaaaannnnnn......

What a dissappointment. Know that you are in my thoughts.

Obviously, a change is needed. I would not stop tx abruptly without first talking about changing interferons, etc. with either your current doc or another.

You may consider emailing Dr Cecil for an opinion.

[LvdByGod]

MAN AT LEAST GET A SECOND OPINION... SOMEONE AT A LARGE HOSPITAL...of course a hepatologist...they may know how to get you the infergen...for non responders...

THE BEST THING TO DO WOULD BE START INFERGEN AND SEE IF THAT GETS IT DOWN...BUT YOU GOTTA DO SOMETHING STRONGER NOW...

don't forget the meds are stong/cause there own problems so staying on for 24 more weeks if its not working is probably not very wise...not that i wouldn't give it a couple more months if that's all the choice i had...

YOU REALLY SHOULD GET THAT BIOPSY...they are not that bad as long as it is ultrasound guided by an experienced hepatologist... cause if you have a stage 0-1 than you will know how serious to be about continueing.

will he let you do extended treatment if you show clear on your next pcr. you could go a year past your first clear...by the way i certainly wouldn't wait too long to get the next pcr...you gotta keep an eye on it...it should be long gone by now...

my prayers are with you, may God bless you and heal you!

sandi

[Tyree2005]

Hi Sandi,

Have you been away I have relly missed you and hope you are well.  I will be starting tx tomorrow if my meds come.  They did not come today but hopefully tomorrow.  Keep your fingers crossed.
Much Love to you all
Tyree

[strator]

I wish there was a magic button for all this. I hope your journey eases. It's chapel night for me. I'll keep you in my thoughts.
Don

[beamishboy]

Man o man o man!!! i feel for ya........any change in trx frm week 12 to 24??will Doc up your dosage?? i mean initially your #'s were going great guns! What's up w/ that? please know i'm rooting for you,keep us updated,o.k.?

[jaroman]

Thank you all for the encouragement. The doc just told me he thinks I should finish the 48 (some people still clear,good for me ol liver cells, blah, blah)/  He wont up my Pegasys and I cannot get any other interferon in Costa Rica.  He will do a biopsy if I push it, but doesnt think its necessary.
Still cannot decide...

[Tallblonde]

I agree with the others who are urging you to get a biopsy.  Personally, I think everyone should have one before making any treatment decisions.  If you have mild damage, it's reasonable (especially in your case) to wait for a new treatment protocol.

I don't understand your doctor's recommendation to go for 48 weeks with a treatment that clearly isn't working for you.  What sense does it make to have you run such a grueling race when the odds for SVR look pretty slim?  

Try not to get too discouraged by this setback.  Re-group and chart a new course: start with a second opinion, then schedule a biopsy, and then make a final decision with this important information.

Good luck to you.  Things will get better.

Susan

[njrsl]

HEY THERE TALL WOMAN!!! I FINALLY got some time on-line and saw yo POST! GREAT !! Thanks for postin !! I was wonderin when you would get to postin again after I saw you fightin awhile back !!!  Whoooo woman... you let loose!!! one perosn after the other!!!!! hahahahha!!!!! i sitll thank your the smartest woman here. Yeah...I stillbeen takin your regiman but thinkin of TX.The liver aint bad but dont wnat to til it is. You shouldnt be embarased about what happen here couple months back. so post more!!!!hahahaha I should be the one that feels pecurlear, Can't remember who now but I called one man here an woman!!! hshshshhs What an insult!! But Im here!!! NOTHING really gets to me anymore. I laugh my way through all of lifes difficulties.  Hahahhaahhaha.
I will put your name "tallblond" on th prayer list tomoorrow at church so you will feel better in comin back more.  Folks are pretty forgivin around here. Even some of the worst women is bein okay now. Hope this makes ya feel better, just passing by and saw your comment!!! n

[cuteus]

the meds are no longer working on your virus, as shown  by the increase instead of decrease of the VL.  Was the test done at the same lab and with the same range as the 12 wk one? If it was, then nothing is going to change if the dosages are the kept the same. No reason to continue with these toxins, if your liver damage is not severe, see about a biopsy. If you are at stage 3 or above, you need more aggressive tx. Even if you continue on present meds to try and  reverse the damage, I don't see how you will, given the fact that they are not affecting the virus significantly.  It is time for a change, drs, meds or both. Please get a bx or a fibroscan if available.

[Tallblonde]

The only reason it may seem like I'm not posting as often lately is because I recently started a new job and I don't have as much opportunity anymore to post during the week. That's why most of my recent posts have been on the weekends.

I'm glad you find my posts so entertaining.  I wish I could say the same about your input.

Susan

[Tallblonde]

Perhaps you'd be taken a lot more seriously on this board if your posts didn't contain 100 exclamation points!!!!  It makes you sound like a 12-year-old girl!!!!!!!!!!

Haaahaahaaa!!!!!!!!!   Giggle-giggle-giggle!!!!!!!!!

Woohooo!!!!!!!

!!!!!!!!!!!!!

See my point?  It's annoying.  Grow up.

Susan

[njrsl]

OMG!!!!!hahahahahahah!!!!! See their tallbroad you can cut some funny jokes wehn you want. That is what it is all about here!!! Thamk you, Isben, she do like to give me mercey!!!! hahahahahahah@!!!!!! I just love you women being funny!!!!!  n

[njrsl]

WOW !!! Good to see you havin fun!!  And bearing humor too !!! X-planation marks!!!!hilarious!!!!! See there woman.... you got it in you!!!! Words cant describe how happy I am to see that you are still posting after that big stuff comin down!!!!! Everone was hatin ya an You showed them! Hahahahah!!!!! I remember your hard times!!!!! Youd been a favorite woman to many men here!!!!  But you did the best you could an have to give you credit for that.
Woman... you kept that Dragon at bay all this time!!!!!!!!!!!!!!!   Congratulations!!!!!  Don't worry about the naysayers an depressin folks!!!! Never look back now. You postings inspire others and do more for them than any "odds" people like to yak about!!!!!  You and me woman and this crazy disease!!!!! hahahahaha!!! I think Im th only one that appreciates your refined since of humor! n