Hepatitis C Community
ANYONE ELSE ON THE 7977+5885 TRIAL?
About This Community:

This forum is for questions about medical issues and research aspects of Hepatitis C such as, questions about being newly diagnosed, questions about current treatments, information and participation in discussions about research studies and clinical trials related to Hepatitis. If you would like to communicate with other people who have been touched by Hepatitis, please visit our new Hepatitis Social/Living with Hepatitis forum

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

ANYONE ELSE ON THE 7977+5885 TRIAL?

I'm on day 9 of 7977/5885 no riba for 24 weeks.

Anyone else out there??
22 Comments Post a Comment
Blank
Avatar_f_tn
I'm going to keep bumping this up for a while. Hoping others on this trial will see it and post.
Blank
1707536_tn?1334977677
Yay UKgirl. Curious about your VL tests...

I know someone on another forum on this trial with riba for 12 weeks. Will send her the link.
Blank
Avatar_f_tn
Hi, thanks Katla for the link.  I am on the 12-week, Riba arm.  My VL came down from 1,470,000 to 163 w/in a 10-day period.  Have you had any sides?  I think most of my sides have been from the Riba, but it's hard to tell.  

Sandy
Blank
Avatar_f_tn
Going in on Tuesday Katla, to get my first week VL results.
Blank
Avatar_f_tn
Hey Sandy. If you're HepSandy from the other link, we're already talking ;-)
I'll PM you here.
Blank
2035311_tn?1332683577
I was on 7977, BMS520079, an riba.  Some sx were:  Little stomach upset the first week or so. Slight light headedness for a few seconds after taking 7977 for the first week or so. Slight cough from the riba lasted unti 5 weeks post tx. It came and went. from the riba.  I kept a journal if you want more info.

Good luck!
Blank
Avatar_f_tn
  Hi UKgirl, congrats on your 9th day Treating :)
I'm sorry, but I was distracted with my own Tx, during many of your posts, but I am interested in this Trial you are in.
   Can you tell me what genotype you are, your Stage of liver damage, and if you have Treated before?
I'm sorry, I should have it memorized, since I read your posts, but I was mainly focused on the Triple Tx posts~
  I would much rather have the rest of my friends and family, who have Hep C, do the Interferon Free Tx's.
   One more question:  Do you, or anybody else reading this,know if there is a chance of you becoming tolerant to the new generation of DAA (7977 aka  Sofosbuvir) in this study, and if this happens, what the research Docotrs plan on doing, if this happens?
   This is my husbands fear, so he is staying away from these double blind studies~
Blank
1707536_tn?1334977677
UKgirl, just remembered someone else. Will pm her shortly.

Boceprevirgal- UKgirl is NOT on a double blind study; it's open label, i.e. everyone knows what drugs they are on.

And as far as resistance, the new drugs are said to have a high barrier of resistance but no one really knows yet which was one of the reasons I was so worried about doing my trial.
Blank
Avatar_f_tn
  Yes,  you are smart to think ahead, and thank-you for that imfo
Blank
Avatar_f_tn
Genotype 1a. High VL, tx naive, IL28b CC. According to my fibrosure test (blood test) F0. Had the virus for 35 years....very, very lucky!

Blank
Avatar_f_tn
  Oh, that is great.  I'm also glad you avoided the Interferon, and the Ribaviran is no picnic either~
Good Luck, this is exciting
Blank
Avatar_f_tn
When I screened for the trial, my VL was fourteen million. Yesterday my trial nurse called me. The results of ONE WEEK of treatment and my VL was down to 53!!!!!!!!

HAPPY THANKSGIVING TO EVERYONE!
Blank
1707536_tn?1334977677
I just came on to see about your VL. So happy to read this...
Blank
Avatar_f_tn
Have you hit your SVR 12 yet katla? Feel like I'm really behind on the 7977/BMS 12 week trial. Do you know how anyone else did on the same trial?
Blank
1707536_tn?1334977677
yeah...I'm anxiously awaiting the results from my (almost) 24 weeks post...should have it early next week.I couldn't get much information from my trial coordinator. I know they had 9 subjects/patients, my guess is 6 on the 12 week, some with and some without Riba. I know not everyone is clear but she said they were happy were the results.
Blank
Avatar_f_tn
Where does the time go?? I'm sure you'll be fine Katla. Can't wait to hear the good news. I wonder which ones didn't make it.
Blank
Avatar_f_tn
Just got my second week blood work results.....

UNDETECTED!!!!

Wanted to let you all know that these drugs ARE doing the trick!!!

Oh.....and NO riba!!!
Blank
163305_tn?1333672171
AWESOME !!!! I am so very very happy for you and for the future of hep C treatment.
Blank
1707536_tn?1334977677
AWESOME INDEED!!!! That's really amazing.

Not to steal your thunder (or whatever the expression is) but my 24 week post tx pcr was undetectable (it was actually a little less that 24 2wks)
Blank
163305_tn?1333672171
Wonderful news !
These new meds are working !!!!!!
Blank
Avatar_f_tn
Oh Katla.....that's not stealing my thunder....It's just adding to the joy and the celebration!!!!

How wonderful!!!!
Blank
2084772_tn?1332406698
oh my old friends! hi everyone and yes im undetectable at 6 months post too! good luck with your trial ukgirl!!! second week undetectable, amazing :D
hi katla! i was told, i thought anyway, that every one on our trial was und at 6 months post- no?
Blank
Post a Comment
To
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Hepatitis C Community Resources
RSS Expert Activity
242532_tn?1269553979
Blank
Emotional Eating Control: How to St...
Aug 28 by Roger Gould, M.D.Blank
233488_tn?1310696703
Blank
New Cannabis Article from NORTH Mag...
Jul 20 by John C Hagan III, MD, FACS, FAAOBlank
242532_tn?1269553979
Blank
3 Reasons Why You are Still Binge E...
Jul 14 by Roger Gould, M.D.Blank