Aa
A
A
Close
691935 tn?1421030690
Acute vs. Chronic in Hep C ??
I actually posed this question in Rick444's earlier post.  This may be a dumb question, but if a person tests posibve for HCV and has a VL how could that be diagnosed as Acute?  What test would confirm this?  
Cancel
6 Answers
Page 1 of 1
87972 tn?1322664839
Not a dumb question at all. The diagnosis of acute HCV is a tricky one, I believe. It involves the diagnosis of HCV with a positive RNA result, along with patient stated risk factors. The patient can also have certain characteristics; fever, jaundice, and *extremely* high liver enzymes *may* be present. In other words, the patient *might* present with symptoms, where with chronic HCV, the disease is essentially asymptomatic. The acute phase only lasts up to six months after exposure; after that, it’s considered chronic. There is no actual test, other than an HCV RNA that will diagnose acute HCV; that’s why it’s unusual to find.

Bill
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
Acute stage is a time period of approximately six months after being infected. Because the majority of people have an asymptomatic acute phase, most end up being diagnosed in the chronic stage after a routine blood test or perhaps trying to donate blood. Some, however -- I include myself-- had a symptomatic acute stage (fever, jaundice, etc) -- so the diagnosis was easy. The acute stage is also characterized by sky high liver enzmes (could be in the thousands) and often intermittent viremia meaning that the viral count can go from UND to detectible to UND and so on. 40% of women and around 15-20% of men will clear the virus naturally during the acute stage.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
691935 tn?1421030690
Thanks - interesting.

So, Rick4444, must have been infected within the last 6 months as he stated the diagnosis is acute ?

And, Jim you also were acute?

Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
And, Jim you also were acute?
----------------------------------------------
Everyone with Hep C is acute during the first six months. In my case, I had a symptomatic acute stage while most have an asymptomatic acute stage. The difference with Rick is that he has an opportunity to treat during the acute stage while I didn't because Hepatitis C wasn't "discovered" back then. For that reason I ended up treating close to 40 years later in of course the chronic stage.

-- Jim
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
691935 tn?1421030690
I see - thanks again.

-Stacie
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
Probably should modify my first sentence somewhat to read that everyone who has chronic Hep C had an acute stage during the first six months. There are also some who clear the virus naturally during the first six months and therefore once they clear they no longer have Hepatitis C. Also, at least one study shows that more people than previously thought actually clear the virus naturally *after* the acute stage and possibly even years later although statistically still quite a minority.

-- Jim
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Your Answer
Avatar universal
Answer
Do you know how to answer? Tap here to leave your answer...
Answer
Answer
Post Answer
A
A
Recent Activity
Avatar universal
Blank
Day 5
3 hrs ago by Amber98
189897 tn?1441130118
Blank
Sandman2 commented on Anxiety disorder - am...
15 hrs ago
317787 tn?1473362051
Blank
Dee1956 DA DA DA!!! 105 and a half... Comment
21 hrs ago
Blank
Weight Tracker
Track your weight over time
Start Tracking Now
Top Hepatitis Answerers
317787 tn?1473362051
Blank
DC
163305 tn?1333672171
Blank
Rural Mural, CA
446474 tn?1446351282
Blank
San Francisco, CA
Avatar universal
Blank
1747881 tn?1358189534
Blank
Greeley, CO
2059648 tn?1439770265
Blank
Hepatitis C Community Resources