Aa
A
A
Close
691935 tn?1421030690
Acute vs. Chronic in Hep C ??
I actually posed this question in Rick444's earlier post.  This may be a dumb question, but if a person tests posibve for HCV and has a VL how could that be diagnosed as Acute?  What test would confirm this?  
Cancel
6 Answers
Page 1 of 1
87972 tn?1322664839
Not a dumb question at all. The diagnosis of acute HCV is a tricky one, I believe. It involves the diagnosis of HCV with a positive RNA result, along with patient stated risk factors. The patient can also have certain characteristics; fever, jaundice, and *extremely* high liver enzymes *may* be present. In other words, the patient *might* present with symptoms, where with chronic HCV, the disease is essentially asymptomatic. The acute phase only lasts up to six months after exposure; after that, it’s considered chronic. There is no actual test, other than an HCV RNA that will diagnose acute HCV; that’s why it’s unusual to find.

Bill
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
Acute stage is a time period of approximately six months after being infected. Because the majority of people have an asymptomatic acute phase, most end up being diagnosed in the chronic stage after a routine blood test or perhaps trying to donate blood. Some, however -- I include myself-- had a symptomatic acute stage (fever, jaundice, etc) -- so the diagnosis was easy. The acute stage is also characterized by sky high liver enzmes (could be in the thousands) and often intermittent viremia meaning that the viral count can go from UND to detectible to UND and so on. 40% of women and around 15-20% of men will clear the virus naturally during the acute stage.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
691935 tn?1421030690
Thanks - interesting.

So, Rick4444, must have been infected within the last 6 months as he stated the diagnosis is acute ?

And, Jim you also were acute?

Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
And, Jim you also were acute?
----------------------------------------------
Everyone with Hep C is acute during the first six months. In my case, I had a symptomatic acute stage while most have an asymptomatic acute stage. The difference with Rick is that he has an opportunity to treat during the acute stage while I didn't because Hepatitis C wasn't "discovered" back then. For that reason I ended up treating close to 40 years later in of course the chronic stage.

-- Jim
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
691935 tn?1421030690
I see - thanks again.

-Stacie
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
Probably should modify my first sentence somewhat to read that everyone who has chronic Hep C had an acute stage during the first six months. There are also some who clear the virus naturally during the first six months and therefore once they clear they no longer have Hepatitis C. Also, at least one study shows that more people than previously thought actually clear the virus naturally *after* the acute stage and possibly even years later although statistically still quite a minority.

-- Jim
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Your Answer
Avatar universal
Answer
Do you know how to answer? Tap here to leave your answer...
Answer
Answer
Post Answer
A
A
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
What Is Hepatitis C?
Learn about this treatable virus.
image description
Diagnosing Hepatitis C
Getting tested for this viral infection.
image description
Just Diagnosed? Here’s What’s Next
3 key steps to getting on treatment.
image description
Understanding Hepatitis C Treatment
4 steps to getting on therapy.
image description
Your Guide to Hep C Treatments
What you need to know about Hep C drugs.
image description
Managing Side Effects of Treatment
How the drugs might affect you.
image description
Making Hep C Treatment a Success
These tips may up your chances of a cure.
Recent Activity
406584 tn?1399591666
Blank
10356 Coyote is always out there ... Comment
16 hrs ago
406584 tn?1399591666
Blank
10356 commented on stilltrying1965's status
16 hrs ago
406584 tn?1399591666
Blank
10356 commented on landbray's status
16 hrs ago
Blank
Weight Tracker
Track your weight over time
Start Tracking Now
Top Hepatitis Answerers
Avatar universal
Blank
317787 tn?1473362051
Blank
DC
1747881 tn?1358189534
Blank
Greeley, CO
683231 tn?1467326617
Blank
Auburn, WA
7469840 tn?1409849436
Blank
San Diego, CA
Avatar universal
Blank
Hepatitis C Community Resources