Better Results for GT3 Patients

[mac790]

Hey Everyone, This Healio.com website is free, and you don't have to be in the health care field, all you need to do is register. IMO, it is the best site on the Net for HCV info, especially their "HCV Next" publication. In the most recent edition of "HCV Next", there are some very encouraging results for a combo tx regimen for GT3:

http://www.healio.com/hepatology/hepatitis-c/news/print/hcv-next/%7Bda968424-d106-40a0-8dd8-437c659b3e32%7D/recent-approval-holds-promise-for-genotype-3-but-hurdles-anticipated?utm_source=maestro&utm_medium=email&utm_campaign=hepatology%20news

Although less common in the US, it is my understanding that GT3 is much more diffficult to eradicate and more pathogenic than the most common US GT, 1/1a. Looks like an 88% SVR w&w/o cirrhosis, which is a good 20%+ higher than previous methods of tx. If you happen to have GT3, good luck & I hope this might be your ticket to board the SVR train.                 mac790

[rpwoodard]

Mac790,
Thank you so much for the link to Helio.com.
This site has an AMAZING wealth of information! YEs, it has pharmaceutical ads, but authors of the articles list their disclosures / affiliations.

I've been browsing and already found 3 research articles that I'll discuss w/my friend's liver transplant team.
Inspired

[patra_]

Sounds good, plus, I am wondering if those treatments in the past are the reason you have never progressed beyond F2 instead of going on to cirrhosis.  Also, as you said, no struggle/ fight with the Ins Co!

Have they mentioned side effects?  Seems that each new med has fewer and less severe sides - as long as they don't jump back to some of the older ingredients!

Praying for the correct answer to come to you!

Blessings,

Pat

[susan400]

Thanks, Kim.  Still not 100% decided, but so far this trial seems like it would be a good one, unlike skme I've done in the past. No placebo..open label, etc. Will know more one it actually opens up and has the whole protocol spelled out.

[Livelife777]

Hi there and good to see you back.  Wanted to say that I truly believe you've had such "Bad Luck" in terms of treatment.  I honestly cannot imagine going thru tx as many times as you have without success.  I admire your strength to keep pushing forward and reconsider beginning again.
Just wanted you to know that I do hope and feel that with the new advances  in Tx that your time is near.
Best to you
......Kim

[susan400]

Did you complete this tral, or did you get in it?? Naybe I missed it if you had a more recent update?  I got contactex by a clinical trial site about a potential upcoming trial using these drugs w/ or w/o Riba...open label, no placebo, that is supposed to allow protease failure patients, as well as Sovaldi failures. Don't have anymore details about it, just that it's supposed to be coming up in about 1-3 mon. timeframe. It's a 12 wk dosing w/24 wk follow-up.  Don't yet know if it's something that I will be ready or willing to do, but it sounds like a good trial.  The appealing part is not having to fight and argue and plead to get ins to pay for it, since I don't advanced enough liver disease yet.  The unappealing part is the not knowing if it will cayse more harm than good and the extra labwork involved.  The whole thing for me right now is this all feels like a 'crapshoot'.  If I had cirrhosis it would be easy to say 'treat it', but since I've been never advancing past stage 2 in the 32 years I've had this,  it really leaves me questioning what if anything I NEED to do.  Just wondering, Mac if you did use these Merck meds abd if so, did you havd any particular observations w/side effects, hdadaches, sleep, etc.?

[Livelife777]

Thanks Mac for always keeping us in the loop with these current findings.
Hoping your health will continue to find the way.
.....Kim