Please help. Ive jsut been diagnosed. I do not know what my numbers mean. My ui is 15 and my hcv rna is 141. Please help and avise
Im off my treatments as of yesterday FRI so how long b4 you feel better?
Couple of things......Are you treating with a knowlegable doctor ,either a gastroenterologist(experienced in the treatment of HCV) or a Hepatologist.
Quite frankly it does not sound like it,....as a geno type 1 you should have been made avail .the triple therapy of Inf/Riba and either Victrelis or Incivek rather just the combo of Inf. /Riba alone,
Also if this current doctor did your first PCR at week 14 this was not in your better interests,as the week 12 point is the usual cut off point for having viral load and gauging how successful you would be.
Never like to be the bearer of bad news,however given you still have a viral load at week 14 your chances of success are very low,and for your doctor to say he will continue for up to 60 weeks with this result is never recommended .
My advice would be to get referred to a experienced specialist .right away and get their advice on whether to continue at this time with one of the new meds added (as others have suggested ) or to stop now and give it some time and go at this again with the proper drug regime.
Best to you...
Will
Has your Dr. talked about triple therapy? Just wondering since if you're at 15 weeks, you were definitely in the time frame to have those available to you. How are you other labs, like your CBC? They should be monitored regularly for drops that may need to be addressed promptly.
My two cents anyway - from what you've posted, I'm not convinced your Dr. has your best interests, meaning SVR, in sight. Extending to 60 weeks and still being detectable at 15 in really old school in light of the new meds available.
If it were me, and knowing what I know now after learning so much on these forums, I would stop and regroup for now. First and foremost, I would find an new Dr. to guide my treatment plan, one that is up on all the new developments in managing HCV and liver disease.
I'm not sure what the options are as far as introducing one of the new meds at this point - hopefully someone will chime in on that question. Extending to 60 weeks of the old meds seems unwarranted to me. I did 72 a couple years back because that's what it was at the time for cirrhotics like me. But it can be a lot of wear and tear on the body unless absolutely neccesary.
What are your Dr.s plans for future PCR's if you continue?
Best wishes in moving forward, Pam
yes This is the first PCR test
well I went to Doc and he WAS gonna take me off but I talked him into at least 4more wks.My VL is 1728 n he said it HAS went down from in the THOUSANDS to 1728 he said it has went down and thats good but he says he might keep me on up to 60wks,,,IF he does take me completly off he s talkin like starting back in 6months but to be honest if he takes me off I doubt if I do the treatment again,,,Im pretty down about this but Hey its wat it is,,right,,,
wistuk
This is all very confusing but it appears that you do have detectable virus -- was that your 12-week test, and the only one?
Please do not let your doctor take you off of treatment. Tell us your pre-treatment VL. You sound like an excellent candidate to start with the third medication - a protease inhibitor. I bet either one could knock out those remaining virons in nothing flat.
My first treatment I had detectible virus at week 12 and relapsed but with these new PIs I was undetectible after two weeks on the PI (Victrelis). How has your hemoglobin been? (HGB on your CBC)
When you talk to your doctor today tell him you want to start with a protease inhibitor -- either Incevik or Victrelis.
frijole
Is this the first PCR they've run or were there earlier ones??
Well today at 5pm i will find out if my doc is gonna make me stop my treatments...... :( His nurse called me yesterday afternoon and said Doc dont like the numbers...I sure hope i can finish this out and he dont take me off..im half done...grrrrrr
This result was obtained by RT PCR amplification and analysis by
fluorescence hybridization with probes designed to detect a target
sequence of the HCV genome (Abbott RealTime HCV Quant ASR). This assay
has a reportable range of 20 to 10000000 IU/mL. Titers above or below
this range will not be accurately quantitated.
This assay utilizes Analyte Specific Reagents (ASRs) and has not been
cleared or approved by the U.S. Food and Drug Administration. The FDA
has determined that such clearance or approval is not necessary. ASRs
are used in many laboratory tests necessary for standard medical care
and generally do not require FDA approval. This test was developed and
its performance characteristics determined by ACL Molecular Pathology
Laboratory. This laboratory is licensed and or accredited under CLIA
and the College of American Pathologists (CAP).
Yes Hep C 1a. I will be talking to my doc for sure now. You got me curious and I sure dont wanna be doing this for NO REASON/not getting all meds to get rid of this thats for sure. Thanks Im gonna check out this out.
Those are some weird results? It doesnt make sense. If you still have virus present, you'll probably need to add one of the new drugs (Incivek or Victreles (sp?) to the mix. Are you hep C 1a or 1b? If u have hep C, I wonder why they didn't start you with the new drugs from the start. Weird, I'd ask about that.
Im at wk 15 take Ribovirin tab 2times a day and mondays I do my pegysus/intrerferon shots
Yes.. that is the measuerment they use to quantify VL per ml of blood. Very odd report.
At what week are you in treament and on what meds?
Will
My Doc is not in this wk so I haven't the foggiest idea what any of it means so I guess I will have to wait til he gets back to find out. So what does the viral load mean? That thats how much of the Hep C I have? Thanks Will
1728IU/ML & 3.24 Log mean the same thing ...you have a viral load of 1728...I am not sure why the test says Not Detected. What was the doctor"s interpretation?
Will