Aa
Calling geno 3's
This is a continuation on the thread that Dominic started regarding Steatosis and Geno 3's. A lot of info on steatosis is at: http://www.medicinenet.com/fatty_liver/article.htm
The study that Dominic came up with stated that geno 3's had a chance of NASH (non-alcoholic steatohepitis) in 74 % of us. Wow. My new doc (a Hepotoligist) knew right off I was probably afflicted with both hep C and fatty liver disease. After reading the indicators, I agree with him. (My Infectious disease doc never put this together by the way.) My hep doc said I needed to lose weight before next tx due to suspected insulin resistance. So, now I know I have to deal with both HEP C and NASH. I am wondering how many 3a's out there have relapsed; AND have fatty liver disease? All of us? If so, what are the statistics of clearing after retreating? I wonder if this may be the peice of the puzzle that will lead to a successful SVR.
The study that Dominic came up with stated that geno 3's had a chance of NASH (non-alcoholic steatohepitis) in 74 % of us. Wow. My new doc (a Hepotoligist) knew right off I was probably afflicted with both hep C and fatty liver disease. After reading the indicators, I agree with him. (My Infectious disease doc never put this together by the way.) My hep doc said I needed to lose weight before next tx due to suspected insulin resistance. So, now I know I have to deal with both HEP C and NASH. I am wondering how many 3a's out there have relapsed; AND have fatty liver disease? All of us? If so, what are the statistics of clearing after retreating? I wonder if this may be the peice of the puzzle that will lead to a successful SVR.
From what I understand, fatty liver can be cured? from successful treatment. But wonder how much it effects reaching SVR. Congratulations on clearing.
Im geno 3, fibrosis 2 (was 3 b4 tx), tx in 2004, Relapser. I had fatty liver before treatment, but it hasnt shown up in 2 biopsies since treatment.
its great to have another dedicated seeker! it has been known for some time geno 3 association with steatosis. with 3 negative predictors i was lucky...and cleared.
50+y/oF, geno 3a-viral load >20 mill, bx F1G2 with mild steatosis, infection >20yrs.
?numbers but LDL,HDL and triglycerides all in abnormal low range pre-tx. 6months later all back to mid normal range and actually took measures to >HDL.
6months tx with wt based peginterferon and ribavirin 1000mg.
rvr 4wks pcr, undetected all through. svr dec 2006
would i do it again? yes, yes, definitely yes. i'm free
50+y/oF, geno 3a-viral load >20 mill, bx F1G2 with mild steatosis, infection >20yrs.
?numbers but LDL,HDL and triglycerides all in abnormal low range pre-tx. 6months later all back to mid normal range and actually took measures to >HDL.
6months tx with wt based peginterferon and ribavirin 1000mg.
rvr 4wks pcr, undetected all through. svr dec 2006
would i do it again? yes, yes, definitely yes. i'm free
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