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475555 tn?1469304339

Comparison of 2013 DAA trials

Hi, Medhelpers!

I was reading over the online articles in a supplement to Liver International devoted to the 2013 Paris Hepatitis Conference. I found a chart comparing the 12-week SVR rates of all (or most) of the IFN-free DAA treatments in trials in 2013. I thought the chart would be interesting to the forum so I'm posting it here. It's the first pic in My Photos.

Note that the chart shows only data from trials of Tx-naive GT1 subjects. There's another chart in the article for trials of Tx-experienced subjects, as well as a lot of other information on the new drugs:

"HCV direct-acting antiviral agents: the best interferon-free combinations", in Liver International - Volume 34, Issue Supplement s1 - Proceedings of the 7th Paris Hepatitis International Conference on the Management of Patients with Viral Hepatitis, 13–14 January 2014.
http://onlinelibrary.wiley.com/doi/10.1111/liv.2013.34.issue-s1/issuetoc

I hope this is useful to people.

Cheers!

Mike
4 Responses
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475555 tn?1469304339
Thanks for the CCO pointer, pooh.
Helpful - 0
1815939 tn?1377991799
That is a helpful chart and it is an easy reference to see how the DAAs are doing for GT 1 treatment naive.

Clinical Care Options has a good slide presentation on the various new treatments and it is worth reading/looking at.  People can just go to Clinical Care Options, register if they are not already registered, and type in the title into the search box.

The title is:

Clinical Impact of New Data on HCV Investigational Agents From the 2013 AASLD Meeting

It gives the results for both treatment naive and treatment experienced GT 1 and also for GT 2 and 3.

Helpful - 0
475555 tn?1469304339
Cool! Thanks!

M.
Helpful - 0
1747881 tn?1546175878
Helpful - 0
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