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you have crossed from a deer in the headlights to a light at the end of the tunnel that isn't a steamroller....feels pretty dog gone good doesn't it!!!
I beat cancer 15 yrs ago, and that "all clear" news is hard to beat.
Hope you have someone to celebrate with !!!!
mb (@wk77)
Teuf
I am thrilled for you.
Stay well,
Mike
All my very best wishes,
Port
May the healing continue.........Pam
smaug
Bill
Blessings
Goldyn
I wish you a beautiful hepc c free life!!!!
Marcia
Great song, too.
Isobella
I am so very happy for you! You did it! Perserverance beat the virus! This is good news for everybody else who is/was detectable but not quantifiable at week 24. Enjoy your virus free life!
Hugs,
Za
schuss.
ca
Wish you a free life now!
Be well.
Charm
Perhaps Arase et al. are on the right way indeed? Well, one single case (me) without a control is no evidence, but another hint.
My deep solidarity is with all of you, who still have to fight.
Best wishes, drofi
Arase et al., Inter Med 47: 1301-1307, 2008
The aim of this study was to determine the suitable treatment period in patients who achieve virological
response during combination therapy of peginterferon and ribavirin for chronic hepatitis C virus infection.
Methods: Inclusion criteria were HCV-genotype 1b, serum HCV RNA level of 100 KIU/ml before treatment,
and negativity of serum HCV RNA during treatment. The 366 patients were enrolled in this retrospective
cohort study. Patients were classified into four groups according to difference of response: rapidvirological
response (RVR) at week 4 after the initiation of treatment (n=37), early-virological response
(EVR) at week 5-12 (n=161), late-virological response (LVR) at week 13-24 (n=131), and superlatevirological
response (SLVR) at week 25-48 (n=37). A non-relapse in patients with undetectable HCV RNA
during therapy was defined as clearance of HCV RNA 6 month after the cessation of therapy.
Results:
Of the 366 patients, 241 had non-relapse and the non-relapse rate in each group was 89% (33/37)
in RVR, 79% (127/161) in EVR, 54% (71/131) in LVR, and 27% (10/37) in SLVR. In RVR, 26 of 27 patients
with continuance of negative HCV RNA of 30 weeks during treatment had non-relapse. In EVR, patients
with period of negative HCV RNA of 40 weeks had non-relapse rate of 90% (71/79). In LVR and
SLVR, all nine patients with continuance of negative HCV RNA of 60 weeks had non-relapse.
Conclusion A suitable treatment period of combination therapy for chronic hepatitis C should be determined
based on the time of attainment of negative HCV RNA.
-- Jim
Really happy for you.
More evidence is accruing that treating for 44 weeks or so past UND is getting good results.
Anecdotal evidence is still evidence drofi.
CS
And I think you're absolutely right about Arase; newbies routinely ask how Drs came up with 24 and 48w. Determining tx duration from evidence seems such a duh-concept it's really remarkable it's just surfacing now (the trouble with Drusano was that it was based on retrospective statistical modeling of standard-length tx).
Anyway, you're free now - enjoy!