Hepatitis C Community
Elevated AFP
About This Community:

This forum is for questions about medical issues and research aspects of Hepatitis C such as, questions about being newly diagnosed, questions about current treatments, information and participation in discussions about research studies and clinical trials related to Hepatitis. If you would like to communicate with other people who have been touched by Hepatitis, please visit our new Hepatitis Social/Living with Hepatitis forum

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

Elevated AFP

First it was the 64 week VL 'blip' of 18 IU/ml.  The good news is the 68 week VL retest came back und <5!  A breather.  (For those who are continuing to read and don't know me, I'm the caregiver to my husband stage 4, geno1, doing 72 weeks.)

But less than a week's reprieve, and I'm getting slammed against the wall again.  Hubby's nurse called today to report that his AFP was not good:  six months ago it was 25, three months ago it was 46, and last week it was 128.  (We haven't seen numbers like that since his HCC re-section in 2007.)  The nurse mentioned 'tp' again for the first time in months...

And here it was my husband was thinking he could go to 6 month intervals between CT-Scans, but the lab results are dictating otherwise.  It's good yet somewhat unsettling when you're told the doctor's booked solid for the month but he'll squeeze you in next week.  

Has anyone had AFPs in the hundreds with good outcome?  (Besides beloved mike&walrus who went to TP ... I know it's a long stretch here, but wondering if it's not so uncommon for cirrhotics to have triple-digit AFPs in the absence of tumor...)

Back on the not-so-merry-go-round,
~eureka

PS:  Anyone familiar with des-y carboxy prothombin blood testing?
Tags: afp
Related Discussions
8 Comments Post a Comment
Blank
Avatar_f_tn
My husband recently had AFP of 90. It is lower than yours, but still high. His CT scan was clear, and a month later AFP went down to 50. He is not on treatment.

Also the doctor tested some specific fraction of AFP, which specifically points to liver cancer. It was normal.

I wish everything will be OK with your husband. Hopefully, it is just a fluctuation.
Blank
Avatar_m_tn
I have read liver cancer AFP is usually very high. I think I read if it is around the 500 range.
Also I have read where cirrhosis and even just having HCV can cause it to rise.

Wishing your husband the best.
Blank
419309_tn?1326506891
tashka:
It's encouraging to know that high fluctuations do happen to people here even in the absence of tumor.  I did ask his nurse about additional blood testing (AFP L3 and DCP), but she deferred me to wait until we meet with the doc next Thursday.  CT Scan is now scheduled for Tuesday coming, and while I'm certainly hopeful and expectant for a good outcome, I'm also preparing myself for all the possibilities -- including the reality that even the CT Scan may be inconclusive.  Thanks for your response.

copyman:
What you say is very true -- my husband's 2007 hcc was detected because his AFP was >2000, so it was a straighforward diagnosis.  The disturbing flip side is that 30% of the time hcc's don't impact AFP -- yet another insidious trait of this nasty virus. Really glad you're free of it...!  Appreciate your good wishes.
Blank
Avatar_f_tn
Yes, AFP L3 is what Vernon's doctor tested after regular AFP was so high. He said that patients with chronic hepatitis often have elevated AFP, because liver cells die and regenerate constantly.

I understand that you are very concerned. I hope that everything will turn out well. Please, keep us posted.
Blank
179856_tn?1333550962
Hey Eureka I am SO glad that it was just a strange false positive like I had after treatment.  That is such great great great news.  I don't know much about AFP but my mom has had elevated AFP for many years (20 or so) and undergone every test known to man with no results.  Then about two years ago it just went down to normal out of nowhere. I'm just going to go with the fact that you're going to get lucky again and like that first 'blip' it will go down too :)
Blank
419309_tn?1326506891
Thanks for sharing that info about your Mom -- it definitely helped my husband to think about the good possibilities more, as well as the bad.  It's been really tough on him -- this added news on top of tx brain-fog is really doing a job on his focus and concentration!  And I'm going with you on that one:  I really hope you're right and it's just another big fat crazy 'blip'.  Big hugs to you. ~eureka
Blank
Avatar_m_tn
I have cirrhosis and I've seen my AFP rise from 15 to 230 in less than 3 years.  Still no signs of any tumors on imaging studies.  
Blank
419309_tn?1326506891
Glad your imaging studies are clear! Thanks for sharing that info. ~eureka
Blank
Post a Comment
To
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Hepatitis C Community Resources
RSS Expert Activity
469720_tn?1388149949
Blank
Abdominal Aortic Aneurysm-treatable... Blank
Oct 04 by Lee Kirksey, MDBlank
242532_tn?1269553979
Blank
The 3 Essentials to Ending Emotiona...
Sep 18 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Control Emotional Eating with this ...
Sep 04 by Roger Gould, M.D.Blank
Top Hepatitis Answerers
446474_tn?1404424777
Blank
HectorSF
CA
1815939_tn?1377995399
Blank
pooh55811
476246_tn?1418874514
Blank
Marcia2202
Copenhagen, Denmark
317787_tn?1373214989
Blank
Dee1956
DC
163305_tn?1333672171
Blank
orphanedhawk
Rural Mural, CA
96938_tn?1189803458
Blank
FlGuy
South, FL