Interesting history. Sorry about your CPPD. Sounds painful, and I hope they'll find something to help you with that pain that you can take without feeling wiped.
About the beer, I know several who have never treated and say they simply cannot drink a beer anymore, either, because they feel like they've been hit by a truck if they do -- (just one or two will do it to them.) I have also heard that the hep alone can cause you to react differently to drugs, and that would make sense because your liver could be impaired and may not be metabolizing the drug like it should at the recommended dose.
I don't know anything about post-tx (not personally) or how drugs begin to react differently post-tx, but I'm certain they can indeed be very different.
I'll say this much about Flexeril. I had been prescribed Flexeril many times in years passed for acute cervical pain. It worked well for me. I didn't feel great on it, but it didn't wipe my a** totally out, and I could work just fine. Just prior to my diagnosis of Hep C, I had been on another course of it and had been taking it for at least a month. I began to feel like I was dieing. I didn't associate this ill-feeling with Flexeril because I knew Flexeril very well, and it had never flattened me out like that, and so I went to the doc (has just had a CBC done 6 months earlier which was fine). On this CBC, though, my enzymes were up, my platelets, rbcs, and wbcs were down (this is why I was diagnosed - abnormal labs and history of hep in 70s). I stopped the Flexeril because I did not know what this drug might be doing to my liver. My labs (CBCs and liver functions) for at least 10 years previous to diagnosis had been normal every year on annual physical exam.
It could have been the fact that I had had this virus 30 years and was just at the point that symptoms and change in labs was going to occur. What is strange, though, to me is - having been off all Flexeril, all of my labs returned to normal and have been normal since January 2004. I get them done every three months. Also, a recent fibrosure indicated the degree of inflammation and fibrosis has improved since my first biopsy (which was done when my labs were whacky and when I so sick feeling and had been eating all that Flexeril).
In my heart, I swear I think Flexeril was hurting my Hep C liver and was one reason my enzymes shot up and my platelets, rbcs, and wbcs went down. I know I'll never take it again :)
Fibromyalgia? Why?
I have not heard that one. I am a 2-3 liver condition though.
Also my neupogen got low on last TX.
Do you have fibromyalgia?
No, not the case. I get drowsy for sure but also crippled.
Thanks
I took Flexeril for back pain years ago. It knocks me out for 3 days and then I can function okay. It's getting to that 3 days that is really hard. Possibly this is the case for you?