GS 7977

[baddog52]

Can someone who is on GS 7977 trial tell me, if this is just a pill or is it combined with interferon?

[Jenge]

Any known sx for 7977?

[rivll]

Great, so it was well beyond the rumor stage. Thanks for that.
I believe the aim is for this drug to be partnered with another oral and marketed as an interferon free package.

[hrsepwrguy]

What genotype are you ? It will make a difference in what trials are available with GS 7977

[hrsepwrguy]

Pharmasset Announces Final SVR Data from PROTON trial with PSI-7977 in Subjects Infected with Hepatitis C Infection Genotype 2 or 3
-- 24 out of 24 subjects with HCV genotype 2 or 3 achieved an SVR after 12 weeks of treatment with PSI-7977 400mg QD and pegylated interferon and ribavirin

http://www.prnewswire.com/news-releases/pharmasset-announces-final-svr-data-from-proton-trial-with-psi-7977-in-subjects-infected-with-hepatitis-c-infection-genotype-2-or-3-125877113.html

[rivll]

It was initially meant to be part of an all oral, interferon free drug combination.
It won't be used alone, it will be paired with another oral drug. My nurse mentioned though, that it may be used in a clinical study configured with interferon for 12 wks.)

[hrsepwrguy]

GS 7977 is an oral drug currently in trials, it is being tried in several different configurations with several different drugs.

You can search the current trials at this link

http://clinicaltrials.gov/ct2/search