Gilead study GS-US-248-0131 - phase 2 all oral

[OC]

I was screened today for the Gilead Protocol Number: GS-US-248-0131, Clinical Trials Identifier: NCT01435226

http://www.clinicaltrials.gov/ct2/show/NCT01435226?term=gilead&state1=NA%3AUS%3ACA&rank=13

“A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of GS-5885, GS-9451, Tegobuvir and Ribavirin (RBV) Compared with GS-5885, GS-9451 with Tegobuvir or RBV in Treatment-
Experienced Subjects with Chronic Genotype 1a or 1b Hepatitis C Virus (HCV) Infection”

This study also has a sub study (rescue therapy) that involves:

If the study doctor determines that you are not responding to the study drugs, you will be offered additional medications to treat HCV. If you decide to participate and receive the rescue therapy, you will receive GS-5885, GS-9451, PEG and RBV for up to 24 weeks, followed by up to 24 weeks with just PEG and RBV depending on your response to study drugs.

I will know shortly if I will be participating in this study.

What are your thoughts on this trial since this is a randomized, double blind, placebo-controlled study?

peace

[OC]

just finished shot 48 of 48 of the rescue study, plus 2 weeks of all oral study.

5 more days of ribavirin and that's it, go for my last blood test in 6 days.

if i never see interferon again it will be to soon.

peace

[jerialice]

best of results and SVR!

[OC]

that's great news, good luck!!!

[adamben101]

I just finished this trial.  56 weeks total.  8 weeks all oral failed so we added PEG.  Took 4 weeks, but been UND for the past 44 weeks.  Now waiting for all the good tests.

[OC]

week 40 update:

week 10 - <25
week 12 - <25
week 16 - undetected
week 20 - <25
week 24 - undetected
week 36 - <25
week 40 - <25

46 more days if all goes well.

peace

[OC]

:)