Going to interview for BI 201335 Trial

[fullmoon1]

Going to interview tomorrow morning to begin this trial (BI201335).  I've been reading this forum for several months now and have learned alot about what's ahead.  Just wanted to thank you all for posting and sharing your knowledge.

[fullmoon1]

Great information, sounds very promising.  Now I'm getting excited...

[spectda]

good luck
this looks like very powerful stuff:

http://www.hivandhepatitis.com/2008icr/aasld/docs/111108_c.html

" rapid decline in HCV viral load was observed in all patients, with maximal decline 2-4 days after starting BI201335.

• With the exception of 1 patient in the 20 mg group, all participants receiving BI201335 (96.2%) achieved > 2 log10 decline in HCV RNA during the monotherapy period."


http://hepatitiscnewdrugs.blogspot.com/2011/04/bi-201335-positive-phase-2-results.html

"BERLIN, Germany, and RIDGEFIELD, CT, April 1, 2011 – New data presented today at the 46th Annual Meeting of the European Association for the Study of the Liver (EASL) demonstrate the antiviral activity of Boehringer Ingelheim's once-daily oral protease inhibitor, BI 201335, in both treatment-naïve and -experienced patients with chronic genotype-1 (GT1) hepatitis C virus (HCV), the most challenging genotype of HCV to treat. Results from SILEN-C1 show a sustained viral response (SVR) in 71 to 83 percent of treatment-naïve patients who received BI 201335 once-daily plus the current standard-of-care (SOC) [pegylated interferon (PegIFN) and ribavirin (RBV)]."






• 100% of patients in the 48 mg, 120 mg, and 240 mg BI201335 dose groups achieved > 2.8 log10 drop in HCV viral load during the first few days of monotherapy."

[22hamilton]

Good luck with your interview, maybe you could post on here later and tell us how it went etc.