Got Biopsy report......Finally

Got my long awaited bx report.  Not as good as I was hoping but it could be worse.  They rated me a 2-3 on both categories.  I am probably going to assume I am a 3 due to the recent posts of people being one thing and 6 months later something else higher.  Here it goes.

1  Chronic Hepatitis with mild to moderate inflammatory activity and  early bridging septal fibrosis (grade 2-3, stage 2-3).
2.  Perivenular, non-bridging fibrosis
3.  Hepatocellular and Kupffer cell siderosis.


I have no idea what numbers 2 and 3 tell me

Thanks for your input

Pat

[Pdilly]

I noticed that My ALT and AST were higher than the last blood work done.
ALT -105     AST   47

Do they typically go up and down?

[Mister beagle bailey]

Yes, they do go up and down so don't be alarmed.

Beagle

[sfbaygirl]

Could you tell me why one of those ALT or AST is supposed to be higher or lower than the other. I don't understand this. Thanks!

[Kalio1]

Most liver diseases are characterized by greater ALT elevations than AST elevations.  Two exceptions to this rule exist.  Both cirrhosis and/or alcohol abuse are associated with higher AST levels than ALT levels, often in a ratio of approximately 2:1.

Was that what you were referring to?
Brain Fog is visiting here also, so hope I understood your question right!

[sfbaygirl]

Maybe I misunderstood, or Brian Fog heard it, but I was sure someone mentioned that one should be higher than the other. Hopefully someone can clear this up. It's been bothering me since I read it somewhere.

[bobbyullc]

try this site to explain bx results
bobby
http://hepatitis-central.com/hcv/liver/grading.html

[Mister beagle bailey]

Hi,

Never heard that one # should be higher then the other.  Where did you hear this?  Maybe someone will chime in and let us know.

Beagle

[Mister beagle bailey]

Bibby we are talking about the AST and ALT, and that one should have higher #'s then the other.  Do you know why?

Bob

[sfbaygirl]

That's it! Hey you did good! I never would have remembered that. I knew I saw it, just thought Brian was playing tricks on me again.

Thanks!

[sfbaygirl]

Our livers must be happy!  Great news about your HGB. Wow, a 10.8, just wait until it's back to normal, you will be jumping all over the furniture!

[Kalio1]

I would have to research it more to be sure but if both are within normal range I believe it is ok. As you said, they do fluctuate and can be influenced by foods and supplements and acohol. I am certainly no doctor, but that is they way I understand it. Hope this finds you well and gtting better everyday!

[sfbaygirl]

Beagle; So this means you have cirrohous? Why was this good news? I remember people saying these were good numbers.

My Alt was 38 and AST 21 last week. Does this mean I am NOT cirrohotic?

[sfbaygirl]

Since Beagle's #'s are low does this discount the 2:1 rule?

Is there any findings about the reverse? Doc says my enemyes are good, but doesn't explain why, except they are low.

[Mister beagle bailey]

Your #'s are good because the normal range is:

AST  3 to 50
ALT  5 to 80

Also my #'s are good too.

Beagle

[Mister beagle bailey]

Kalio-- That's what we were looking for, thanks.  Last week my AST was 24 and my ALT was 13.

Beagle

[dogdaddyo]

I am hep c pos and on Pygisys (sp?) Rivo therapy (3rd time .. cleared 10 yrs ago. I enjoy a cocktail after work. CRAZY OR WHAT?

[newleaf09]

#2, referring to non-bridging fibrosis is good news.

[comeagain]

How many cocktails have you been taking before writing  in on this old thread ?

Why don`t  you open a new thread instead and ask!!!

If you asking if you can get the virus back if you take a coktail after work the answer is no ,unless you get so intoxicated you go out and share a needle with someone!!

ca

[helpme38]

I had gallbladder surgery a week ago and since then I have been ill, itching, fatigue, nausea.  My doctor tested my blood for liver disease and these are the results:

AST 149
ALT 392
Alk phos 171
Bilirubin total 1.7

I am not a drinker or do I have unprotected sex but I was in Mexico in 2007 and ate at a roadside stand.  I have done some research and it seems I fit into the PBC area unless I am missing something.

[nygirl7]

helpme - you actually stumbled into the hepc  group of the gastro group...most of us only know about that disease and it's treatment.

I don't want you to think anyone is ignoring you...just go to the top of the page and see "forums" and you will find the right one in there!

Good luck.