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220090 tn?1379167187

HCV difference in life cycle?

Does anyone know why it is possible to cure HCV, but not HIV?  It was explained to me as a difference in the virus life cycle, but the explanation given me had some misconceptions that I would like to clarify.
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148588 tn?1465778809
MKAndrew has been researching (and speculating about) HCV for years. He's the first to admit that many of the speculations in his blog during the last 6 years have been dead ends - but he has a great talent for putting many of these issues into easily understood 'layman's' terms. At this point I value his opinion as much as I do many of the 'heavy' doctors.
Helpful - 0
388154 tn?1306361691
What is this is?? !! Is MK Andrews a doctor don´t think so is Cowriter a doctor dont think so,  but if you didn´t know you sure as hell would thought they were when reading this litany.
No they are two amateur docs very knowledgeable I´m sure but still no docs.
We better  hold on here a second are they speculating and mixing own thoughts with medical fact but not clearly telling what is what.

That could be dangerous in my opinion. I really would like to hear what  Dr Dieterish  dr Pearl , Shiffman , Jacobson or Bergs or any other heavy dr thinks about  this kind of presentation (formulation)  and which facts are correct and which are not !

We are all  forum polices sometimes aint we, if  I` m out in the blue here please police me right back.

ca
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220090 tn?1379167187
I have not seen any studies that quantify interferon resistance, but Dr D did tell me that I should treat longer due to my age impacting my ability to react to interferon and stimulate my own immune system.

So it would not be interferon resistance in the strict sense of the word, but does say that our own ability to deliver interferon to the virus and the ability of our immune system to react to interferon and attack the virus play a strong role in the success of our treatment;  perhaps as much or more of a role than the ability of HCV to resist interferon.
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Avatar universal
To me...the term" interferon resistance " would mean a total nul-responder to the drug...someone who does not have a 2 log drop in 24 weeks to me is interferon resistance ...just my 2 cents worth
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Avatar universal
Still waiting for a link from you.
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Avatar universal
Thanks for looking up the thread. I checked it out as well as other links in it and didn't really see anything which showed that 'people' are interferon resistant. I saw many references by those posting about intereferon resistance in reference to the host, but that was all. I've read numerous studies on interferon resistance and have never seen one that referred to the host as being interferon resistant. If there is a study which uses the definition in this context  I'd really like to read it to see how the definiton is arrived at. Thanks again for the link.
ML
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