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I have finished my treatment, well back in Dec."13.  Hopefully someone remembers me so I hear from a familiar friend, I consider all of y0u my friends.  Had an account problem and couldn't use my regular nickname of getnby so now I am xxgetnbyxx, why x? Don't know.  My hep is still active chronic hepatitis and all that goes with it.  I am mad.   Do not know what I did wrong. I did miss some nite doses and I did tell my doc. l also had to cut my hcv meds down due to 1 side effect of a few. Gallbladder may have too come out. Just recently found this GB stuff out. I have another ultrasound scheduled on Mon. 28th. My question is.........what am I to do...to try....my sciatica and arthritis are or rather have crippled me....I am useless and lonely and sick and almost completely insane.  
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Avatar universal
Hi add me to the list also i can totally understand your devestation of your tx not working, but like others have said new tx is available let your body and mind recover then talk about treating again. Also please dont feel isolated and alone, myself and others i'm sure are here for you. Love& hugs Jules x
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Avatar universal
Sorry to hear what you are going through.  I am in the same boat so we will eventually get through this.  Hang in there...exercise..eat right...and get ready for another round
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Avatar universal
Add me to the list of people sorry to hear this. Like has been said newer and easier treatments are here... Good luck
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Avatar universal
I'm sorry that treatment didn't work for you.  My husband is in the same boat.  There are other treatment options available right now, and another new treatment option that should be approved in October of this year.
You will probably need to wait a few more months, rebuild your blood counts, and get over all of the effects of your last treatment before you can start another, but try to see your hepatologist to discuss the options.
Advocate1955
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317787 tn?1473358451
Hi there.  I am so sorry to hear that the tx did not work for you.  Pooh has given you good advice.  Please don't think you did anything wrong.  It is not your fault that the tx did not work,
Take Care
Dee
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1815939 tn?1377991799
I am very sorry that treatment did not work for you. I know it must be devastating.

Did you ever clear the virus (become Undetectable)? Were you Undetectable at end of treatment and then relapsed?

There are new drugs out now and they are having better success in curing Genotype 3. . My suggestion would be to find a good Hepatologist and get an evaluation. You may have to take care of the Gall Bladder first. But find a competent Hepatologist and get an evaluation of your liver and Hep C status. The currently recommended regimen of 24 weeks of treatment with Sofosbuvir and weight based Ribavirin is having good results for Genotype 3. This treatment is much easier to tolerate and has fewer side effects than the Interferon based treatment.

Don't give up. There is treatment available. Get a good Hepatologist and continue to try to rid your self of Hep C.


The new drug protocol is as follows:

III. Genotype 3
Recommended regimen for treatment naive patients with HCV genotype 3, regardless of eligibility for IFN therapy:
Daily sofosbuvir (400 mg) and weight based RBV (1000 mg [<75 kg] to 1200 mg [≥75 kg]) for 24 weeks is recommended for treatment naive patients with HCV genotype 3 infection.

The VALENCE study assessed the efficacy and safety of sofosbuvir (400 mg daily) plus RBV for 24 weeks in 250 treatment-naive (42%) and treatment-experienced (58%) subjects with HCV genotype 3 infection. The overall SVR12 was 84% and was higher among treatment-naive than treatment-experienced patients (93% versus 77%, respectively). These results suggest higher response rates can be achieved with a 24-week duration of sofosbuvir plus RBV than those reported for the 12- or 16-week durations studied in the
FISSION (Lawitz, 2013b) (12 weeks, SVR12: 63%), POSITRON, (Jacobson, 2013c) (12 weeks, SVR 12: 61%) and FUSION (12 weeks, SVR12: 30%, 16 weeks, SVR12: 62%) trials. The primary reason for the higher SVR with extended therapy among treatment-naive patients was a reduction in the relapse rate from 40% to 5%. In sub-analysis, response rates were similarly high among those with (n=45) and without (n=100) cirrhosis (92% and 93%, respectively).


Recommendations for Patients Who are Initiating Therapy
for HCV Infection Genotype 3 or Who Experienced Relapse after Prior PEG/RBV Therapy:

Recommended regimen for HCV genotype 3 PEG/RBV nonresponders.
Daily sofosbuvir (400 mg) and weight based RBV (1000 mg [<75 kg] to 1200 mg [≥75 kg]) for 24 weeks is recommended for retreatment of HCV genotype 3 infection.


http://www.hcvguidelines.org/sites/default/files/full_report.pdf

Pages 22 and 30.
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