High Alkaline phosphatase

Has anyone else experienced a rise in their
alkaline phosphatase(154),

alt(234), & alts(95) after stopping tx?  Hubby has been off procrit & pegasys & riba for about a week now.  

He had terrible leg bone pain during tx.  I read that the procrit & pegasys can mess with bone growth.  I also read that after a broken leg, the alkaline phospatase usually goes up.  I was wonder if his bones might be healing or if there is another problem?  

I noticed the last two months of hubby's tx, his alt & ast levels started going up.  He also started working 7 days a week about that time.  Could the increased work load be affecting him in a bad way?  Also, he stopped taking Milk Thistle, which before tx brought his ast & alt down by 1/2. ?



Any commets or thoughts would be apprecited.

Your,
Shebee

Alkaline phosphatase: An enzyme made in the liver, bone, and the placenta and normally present in high concentrations in growing bone and in bile. Alkaline phosphatase is released into the blood during injury and during such normal activities as bone growth and pregnancy. It is measured in a routine blood test.

...this part was scarrry:

Abnormally high blood levels of alkaline phosphatase may indicate disease in bone or liver, bile duct obstruction, or certain malignancies. The enzyme is often elevated in the leukemic cells in chronic myelogenous leukemia.

Oh, by the way...the nurse just called and said for hubby to stop tx because his liver test were up.  LOL!   I had to inform her that he finished and stopped last week.  She said, "Oh?"
LOL!