Blood tests show that I have a high liver enzyme count. Everything has been ruled out. I had a liver ultrasound (normal); a liver biopsy (normal). No history of hep c or alcohol. What could be causing the high count?
If your current doctor can not discover the cause of elevated liver enzymes, ask for a referral to a specialist in a major academic medical center. They see a lot more complicated patients than average doctor does and have much better ability to make correct diagnosis.
The main thing, do not let them just brush you off with the statement that they can not discover why your enzymes are up. Elevated liver enzymes is the cause for concern, and it is important to make correct diagnosis. You need to get to the bottom of this.
One of the most common causes of elevated liver enzymes is medications. Over-the-counter meds like Tylenol and NSAIDs like Ibuprofen and Naproxen Sodium can also cause elevated liver enzymes. Statins taken for cholesterol often cause elevated liver enzymes and also some common antibiotics.
Exposure to certain toxins in the home or workplace can be the cause also.
Here's an article that lists some medications that can result in elevated liver enzymes:
Oddly enough, ALT and AST are not only produced by the liver. They can be released by almost any inflamed or irritated tissue.
The whole reason they found my Hep C was due to a curious chain of events. I had gone back to the gym after an extended time off, and way overworked myself. Every muscle in my body was so sore and stiff I could barely move.It just so happened that my annual physical exam was 4 days later.
Well, it turns out my ALT/AST were about 20 times the normal level - up around 800 or so. I quickly did some reading on the web, and discovered that the liver is not the only place these chemicals come from.
To make a long story short, have you experienced any muscle trauma recently? If you have, this can greatly elevate the same enzymes. The key is to look for a marker called CPK in the blood. This is present in muscle injury.
In my case, my CPK was skyhigh as well. So, my readings were the result of muscle injury.
So, my enzyme readings were sky high as a result of my severe muscle trauma caused from a foolish workout. I should know better, but hey, we still think we're 20 years old.
In a month, the readings came down to just above the normal range, maybe 5 points for both ALT and AST. They refused to go any lower. My doc said we really should investigate further, I was like, no need to, I work out regularly, probably just continual low-grade muscle injury.
He insisted. And so, here we are, diagnosed. At least now I have a chance to cure it. I am grateful to my doctor for being so persistent with me.
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