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High Uric Acid Levels
I've had High uric acid Levels before Tx and while Txing... I'm having problems with my back it might be Kidney stones.. I'm going to get an Ultrasound to make sure... Is the high uric acid level the cause of my back pain??
How can i lower these levels?? The pain is in the right side kidney area... If it is kidney stones what do i do?? The study nurse might tell me to stop Tx... and i dont want this to happen.. Please help!! thank you!!
TippyClubb funny you mention high uric acid levels!!!
How can i lower these levels?? The pain is in the right side kidney area... If it is kidney stones what do i do?? The study nurse might tell me to stop Tx... and i dont want this to happen.. Please help!! thank you!!
TippyClubb funny you mention high uric acid levels!!!
I'm in the Vertex trial with the placebo arm...and going 48 weeks. My uric acid is slightly elevated (7.9).
My nurse is not concerned either. In fact I mentioned it to her first. I thought it was because I used to drink alchol. She told me it could be a sx of tx. When I googled around I found mention that it could be a sx of chemotherapy drugs. Didn't mention which ones tho, but interferon is used for leukemia and therefore may be considered a "traditional" chemo drug??
I also found mention that aspirin and caffeine can raise levels. And drinking water will help.
Hope things resolve for both of you. Wishing you both well-Izzy
My nurse is not concerned either. In fact I mentioned it to her first. I thought it was because I used to drink alchol. She told me it could be a sx of tx. When I googled around I found mention that it could be a sx of chemotherapy drugs. Didn't mention which ones tho, but interferon is used for leukemia and therefore may be considered a "traditional" chemo drug??
I also found mention that aspirin and caffeine can raise levels. And drinking water will help.
Hope things resolve for both of you. Wishing you both well-Izzy
He doesn't know because I discussed it with him a few days ago. I would assume if his thyroid levels were off they would tell him.
Of course you can. My fasting glucose was not over "their" limit... but it was at 100. I told them "this is high ,even though it is in the so called "normal range" (which by the way, they are thinking of lowering to 100, duh)...
think of it this way, even if your glucose is normal, but your insulin is high, and you compute the homa score , you wll be IR... if your insulin is high.
If you have any of the sympoms , or a family history of diabetes , or both (as with me) you really need to have your IR checked.
With my level of IR , i fell into the less than 20% chance of clearing catergory.... if you have a normal homa (1) then you fall into the 60% chance of clearing. If i had knownn going in that I had a 20% chance, I would have never tx'ed. I could kill my doctor.
Imagine what the results of the trial studies for soc would have been if IR had been addressed. makes you wonder.
bandman
think of it this way, even if your glucose is normal, but your insulin is high, and you compute the homa score , you wll be IR... if your insulin is high.
If you have any of the sympoms , or a family history of diabetes , or both (as with me) you really need to have your IR checked.
With my level of IR , i fell into the less than 20% chance of clearing catergory.... if you have a normal homa (1) then you fall into the 60% chance of clearing. If i had knownn going in that I had a 20% chance, I would have never tx'ed. I could kill my doctor.
Imagine what the results of the trial studies for soc would have been if IR had been addressed. makes you wonder.
bandman
It is probably related to your diet and IR.
I would definitely find out if I was IR. Try to do it as a separate thing from tx.... tell them you believe you are IR because of symptoms you are having, such as high uric acid... google IR and see if you have any of the symptoms, be able to list them to your doc. and tell him that you are aware that metformin is used to treat this condition.
That is IF you have some of the symptoms.
Were either of your parents diabetics?
bandman
I would definitely find out if I was IR. Try to do it as a separate thing from tx.... tell them you believe you are IR because of symptoms you are having, such as high uric acid... google IR and see if you have any of the symptoms, be able to list them to your doc. and tell him that you are aware that metformin is used to treat this condition.
That is IF you have some of the symptoms.
Were either of your parents diabetics?
bandman
By the way Bklyn Boy is also in the same trial as me. Co Writer said high uric acid is not that common during SOC tx. Were kind of thinking high UA could be a sx of the Vertex trial?
I am in the Vertex No Placebo Telaprevir trial. 1000 Riba -180 Peg and 750mg tela 3 x daily .The thryoid issues is in the consent forms I signed. I knew that going in though, from people on this forum. Pretty smart people here.
what tx meds are you on?
I was on soc and read the insert that came with a big time warning about the possibility of serious thyroid disease.... it also said that my doc was required to make sure i was aware of this. Did she? hell no. I brought it up to her . and she was "oh yeah, thats right... but we are keeping a close watch on your thyroid levels"" ... fortunately they were fine, I just felt kind of weird that no one gave me the thyroid disease warning. I don't think it would have detered me from tx, but still... I like to know whats going on and what could possibly occur.
Course I guess if you read all of that , or were told all of it, a lot of people would get cold feet.. lol.
bandman
I was on soc and read the insert that came with a big time warning about the possibility of serious thyroid disease.... it also said that my doc was required to make sure i was aware of this. Did she? hell no. I brought it up to her . and she was "oh yeah, thats right... but we are keeping a close watch on your thyroid levels"" ... fortunately they were fine, I just felt kind of weird that no one gave me the thyroid disease warning. I don't think it would have detered me from tx, but still... I like to know whats going on and what could possibly occur.
Course I guess if you read all of that , or were told all of it, a lot of people would get cold feet.. lol.
bandman
just don't over do it. sardines are good for you, just don't combine them w/ cheese, olives, etc. google "gout" and you cab\n find a list of foods that you need to be careful with,
bandman
bandman
Amazing about the sardines and uric acid - I just read about it.
And I try hard to eat sardines because they're supposed to be "good" for you.
Just shows how complicated nutrition is. Next time I'll have a couple of sardines instead of the entire tin.
And I try hard to eat sardines because they're supposed to be "good" for you.
Just shows how complicated nutrition is. Next time I'll have a couple of sardines instead of the entire tin.
Ok thank you. I am going to get to the bottom of this soon. I will print out Co Writer info in that other thread and take it with me to my private doctor.
Trial people keep telling not to worry, but I have enough sense to know something is bad wrong, or going to lead to serious complications if I don't get this under control. If it was just the high uric acid maybe I wouldn't be so worried but I got a call today ( trial ) and I have other blood work issues going on also. My thyroid is way high AGAIN--seems they can't get it right. Plus everything is too high or too low. I'm a mess. Lol! Its times to get to the bottom of this.
Geez its always something.! Lol ! I have to laugh--trying to stay upbeat.
To: BklynBoy
Sorry for taking over your post but I figure we both have the same isssus going on so need to start another post.
Trial people keep telling not to worry, but I have enough sense to know something is bad wrong, or going to lead to serious complications if I don't get this under control. If it was just the high uric acid maybe I wouldn't be so worried but I got a call today ( trial ) and I have other blood work issues going on also. My thyroid is way high AGAIN--seems they can't get it right. Plus everything is too high or too low. I'm a mess. Lol! Its times to get to the bottom of this.
Geez its always something.! Lol ! I have to laugh--trying to stay upbeat.
To: BklynBoy
Sorry for taking over your post but I figure we both have the same isssus going on so need to start another post.
bbboy,
"I went to the dr for a fasting glucose blood test today and I will get my results next week.. The doctor said he will not check IR unless fasting glucose is abnormal… He said its an insurance thing.."
with all due respect... your doctor is about 5 years behind on this.
Listen to cowriter... take him studies... if he refuses , then find another doctor... don't walk , run!
or pay for these tests yourself, I don't think that they are very expensive... and all you will need is your fasting insulin level... cause you will already have your fasing glucose level.. it is preferable to have them done on the same day... but you can get a rough idea even if they are days apart.
I also noticed that you said you were "hungr
My glucose levels were high, but within the so-called normal level. After showing my doc studiies, he ordered the insulin test as well. Turns out I am extremely IR, almost diabetic, Not obese either.
I also noticed that you said you were "hungry all of the time" at one point, are you still hungry all of the time?? I was... still am at times... guess what, hungry all of the time is a symptom of IR... so is irratibility.. I had both of these... they are much better now that I am on metformin, and tweaking my dosage on a monthly basis.
I also check my blood sugar every morning... it is coming down! I was looking at 120s in the morning, now I am looking at 90-100 range.
IR seems to be a relatively new concept and many docs still operate under the assumption that you area either diabetic or not. Mine appeared to not even be aware of Insulin Resistance.... but was willing to learn.
Tippy - I am unsure what a high uric acid level would be, I can not remember mine but it was very high.... and the night I woke up with extreme toe pain, I had eaten cheese, crackers and sardines before going to bed..... not a good idea. Very painful!
I probably already had a high uric acid level due to IR, and then then the above foods pushed me into a very painful night.
all you need to know is
"She should be. Because a uric acid higher than 5.8 is predictive of poor response to Hep C treatment." thanks cw!
You guys need to learn everything you can... many docs don't want to mess with this as the patients tend to highly emotional , irratiible, and unreasonbable... it is the virus and meds messing with your mind. In addition they realize that if they or one of their staff gets infected with HCV then their career is essentialy over, IF they reveal they are infected. Thats just my opinion.
bandman
"I went to the dr for a fasting glucose blood test today and I will get my results next week.. The doctor said he will not check IR unless fasting glucose is abnormal… He said its an insurance thing.."
with all due respect... your doctor is about 5 years behind on this.
Listen to cowriter... take him studies... if he refuses , then find another doctor... don't walk , run!
or pay for these tests yourself, I don't think that they are very expensive... and all you will need is your fasting insulin level... cause you will already have your fasing glucose level.. it is preferable to have them done on the same day... but you can get a rough idea even if they are days apart.
I also noticed that you said you were "hungr
My glucose levels were high, but within the so-called normal level. After showing my doc studiies, he ordered the insulin test as well. Turns out I am extremely IR, almost diabetic, Not obese either.
I also noticed that you said you were "hungry all of the time" at one point, are you still hungry all of the time?? I was... still am at times... guess what, hungry all of the time is a symptom of IR... so is irratibility.. I had both of these... they are much better now that I am on metformin, and tweaking my dosage on a monthly basis.
I also check my blood sugar every morning... it is coming down! I was looking at 120s in the morning, now I am looking at 90-100 range.
IR seems to be a relatively new concept and many docs still operate under the assumption that you area either diabetic or not. Mine appeared to not even be aware of Insulin Resistance.... but was willing to learn.
Tippy - I am unsure what a high uric acid level would be, I can not remember mine but it was very high.... and the night I woke up with extreme toe pain, I had eaten cheese, crackers and sardines before going to bed..... not a good idea. Very painful!
I probably already had a high uric acid level due to IR, and then then the above foods pushed me into a very painful night.
all you need to know is
"She should be. Because a uric acid higher than 5.8 is predictive of poor response to Hep C treatment." thanks cw!
You guys need to learn everything you can... many docs don't want to mess with this as the patients tend to highly emotional , irratiible, and unreasonbable... it is the virus and meds messing with your mind. In addition they realize that if they or one of their staff gets infected with HCV then their career is essentialy over, IF they reveal they are infected. Thats just my opinion.
bandman
I have read high uric acid causes gout. Mine is now at 9--at what level would it be dangerously high in your opinion. trial nurse said when it gets in the 30's, but I'm not so sure about that.
If we develop gout to to uric acid when we stop tx and the levels go down does the gout go away?
No more salt or cheese for me. Yuk!
If we develop gout to to uric acid when we stop tx and the levels go down does the gout go away?
No more salt or cheese for me. Yuk!
wait till you wake up with excruciating pain in your toe! This is caused gout and is caused by high u.a. levels. And yes, these high levels are not good if you are tx'ing.
I got mine under control by not eating so much cheese, salty foods and sardines!
bandman
I got mine under control by not eating so much cheese, salty foods and sardines!
bandman
I do still have the high uric acid.. I dont know what is causing it... I just need to keep drinking more water... it will lower my uric acid level alittle bit. I never got my uric acid tested until i started tx.. so i dont know if it was ever high.. for u its probably the meds... i cant wait until i stop the tela maybe i can get more sleep.. I need to buy a treadmill like JTRiver.. I need to get off my azz and lose 25 ibs.. 26lbs in a couple months much respect... i need to lose weight and feel great..lol
Well, your pretty feisty today -- good news no stones. Is your level still high?
One of the causes you posted above was excessive alcohol assumption. Very odd --when I was drinking my uric acid was fine, now I'm not drinking and its high. None of the other things apply to me so it has to be the meds.
Anyway you should almost be done with Telaprevir--3 1/2 weeks for me. Yeah !
One of the causes you posted above was excessive alcohol assumption. Very odd --when I was drinking my uric acid was fine, now I'm not drinking and its high. None of the other things apply to me so it has to be the meds.
Anyway you should almost be done with Telaprevir--3 1/2 weeks for me. Yeah !
What’s up guys? I got some good news I just saved a ton of money by switching to geico lol j/k but I really did… good news is the ultrasound came back totally normal, no kidney stones, no gallstones no problems with any organ…Not sure why the pain is still there a little bit, maybe its my liver healing.. My LFTs are normal.. I m slightly anemic HGB is 12.. I still have high uric acid levels.. I did a search
Causes
High uric acid levels can be caused by either excess production of uric acid in the body or by decreased excretion of uric acid in the urine. Specifically, factors that may cause high uric acid concentration in your blood include:
Drugs sometimes used to treat high blood pressure, such as low-dose aspirin and diuretics
Excessive alcohol consumption
Excessive caffeine consumption
Family tendency (genetics), Hodgkin's disease , Hypothyroidism (underactive thyroid), Leukemia , Niacin, or vitamin B-3 , Non-Hodgkin's lymphoma , Obesity, Psoriasis , Purine-rich diet — organ meat, game meat, anchovies, herring, gravy, dried beans, dried peas and other foods , Some immune-suppressing drugs, person with liver disease
I used to drink alcohol every weekend and alot of caffeine..
I’m like 25 – 30 IBs over weight and I do have a liver disease…
The cancer thing I guess I should get screened I do have a family history of cancer. How do I go about doing that..
Co Writer
I went to the dr for a fasting glucose blood test today and I will get my results next week.. The doctor said he will not check IR unless fasting glucose is abnormal… He said its an insurance thing..
When I told u guys that my blood sugar was 40 at one time it was because I was in jail and they didn’t feed me enough I lost 35 ibs in a few months in there I was away for a year.. I felt sick and dizzy so I when to medical in there and I got my blood sugar tested everyday for a week in the mornings at 5:30 before I ate breakfast.. Mind you we ate chow at 4:30 in the afternoon so every time I got my sugar check it was a fasting sugar level because I didn’t eat anything for over 12 hours.. So I think it was my liver storing the sugar.. so when I got out of the slammer I knew something was not normal so I did extra testing and found out I had Hep C.. Also when I got out I was so fcukin hungry I gain 30 ibs in 2 months lol the doctor called me a pig… I could not help it.. lol
PS I sure dam learn my lesson after that experience.. I will even never jay walk again…lol.. There might be something I left out but I m too BD to remember BD as in Brain Dead…
I like long walks in the park to feed the birds :) J/K
Causes
High uric acid levels can be caused by either excess production of uric acid in the body or by decreased excretion of uric acid in the urine. Specifically, factors that may cause high uric acid concentration in your blood include:
Drugs sometimes used to treat high blood pressure, such as low-dose aspirin and diuretics
Excessive alcohol consumption
Excessive caffeine consumption
Family tendency (genetics), Hodgkin's disease , Hypothyroidism (underactive thyroid), Leukemia , Niacin, or vitamin B-3 , Non-Hodgkin's lymphoma , Obesity, Psoriasis , Purine-rich diet — organ meat, game meat, anchovies, herring, gravy, dried beans, dried peas and other foods , Some immune-suppressing drugs, person with liver disease
I used to drink alcohol every weekend and alot of caffeine..
I’m like 25 – 30 IBs over weight and I do have a liver disease…
The cancer thing I guess I should get screened I do have a family history of cancer. How do I go about doing that..
Co Writer
I went to the dr for a fasting glucose blood test today and I will get my results next week.. The doctor said he will not check IR unless fasting glucose is abnormal… He said its an insurance thing..
When I told u guys that my blood sugar was 40 at one time it was because I was in jail and they didn’t feed me enough I lost 35 ibs in a few months in there I was away for a year.. I felt sick and dizzy so I when to medical in there and I got my blood sugar tested everyday for a week in the mornings at 5:30 before I ate breakfast.. Mind you we ate chow at 4:30 in the afternoon so every time I got my sugar check it was a fasting sugar level because I didn’t eat anything for over 12 hours.. So I think it was my liver storing the sugar.. so when I got out of the slammer I knew something was not normal so I did extra testing and found out I had Hep C.. Also when I got out I was so fcukin hungry I gain 30 ibs in 2 months lol the doctor called me a pig… I could not help it.. lol
PS I sure dam learn my lesson after that experience.. I will even never jay walk again…lol.. There might be something I left out but I m too BD to remember BD as in Brain Dead…
I like long walks in the park to feed the birds :) J/K
Thanks for the info! I will have to learn more about this.
I've been trying to reducing my uric acid levels for years now. I have been changing my diet and get a 24 hour urine test a couple of times of year to make sure it is under control.
My cirrhosis is the biggest factor cutting my odds of therapy working plus as of now I don't have enough platelets to due therapy. I go down into the teens at about 12 weeks. So I'm stuck for now.
Appreciate the info and will read up on uric acid and HCV.
Hectorsf
I've been trying to reducing my uric acid levels for years now. I have been changing my diet and get a 24 hour urine test a couple of times of year to make sure it is under control.
My cirrhosis is the biggest factor cutting my odds of therapy working plus as of now I don't have enough platelets to due therapy. I go down into the teens at about 12 weeks. So I'm stuck for now.
Appreciate the info and will read up on uric acid and HCV.
Hectorsf
My uric acid has come back down after EOT
uric acid before tx, was 7.1...
during tx, uric acid jumped around between 8.4- 9.5
IR, homa1.6_ glucose 67-80 (most blood draws around 78)
8 weeks post eot blood draw, my uric acid is now at an all time Low, 5.8...
Glucose went up by 10. not-fasting,but nothing to eat/drink5 hours(as usual) 90...
Probably not significant.
apache
uric acid before tx, was 7.1...
during tx, uric acid jumped around between 8.4- 9.5
IR, homa1.6_ glucose 67-80 (most blood draws around 78)
8 weeks post eot blood draw, my uric acid is now at an all time Low, 5.8...
Glucose went up by 10. not-fasting,but nothing to eat/drink5 hours(as usual) 90...
Probably not significant.
apache
HectorSF thank you for that info i heard kidney stones can be the worse pain ever and i hope it doesn't happen to me.. with my luck im gonna be in the hospital real soon...
I need to drink more water then i already im.. will do... i dont know if i have a family history of kidney stones.. i really dont think so.. that actually the one thing i never heard anybody in my family having but i will talk to some of them today... the back pain is under the rib cage area definitely the kidney area and im pretty sure its kidney stones..
the pain is like a 3 i think maybe more...
Cowriter i have not check yet if im insulin resistant... im gonna make appointment today with the doctor.. one thing im responding pretty well with the HCV treatment.. my 2 week blood test came back UND... I have not checked since than and i did shot 8 yesterday.. when i talk to doctors its like talking to a wall they dont listen u tell them one thing they do the other... i made the appointment for monday nothing sooner...
thank you for the info and the studys...
sorry i dont reply sooner it takes me mad long to type and i feel like im brain dead with the TX lol i cant spell small azz words... other wise i m feeling good still.. i will keep u guys posted... had the ultrasound today results in 1 or 2 days
I need to drink more water then i already im.. will do... i dont know if i have a family history of kidney stones.. i really dont think so.. that actually the one thing i never heard anybody in my family having but i will talk to some of them today... the back pain is under the rib cage area definitely the kidney area and im pretty sure its kidney stones..
the pain is like a 3 i think maybe more...
Cowriter i have not check yet if im insulin resistant... im gonna make appointment today with the doctor.. one thing im responding pretty well with the HCV treatment.. my 2 week blood test came back UND... I have not checked since than and i did shot 8 yesterday.. when i talk to doctors its like talking to a wall they dont listen u tell them one thing they do the other... i made the appointment for monday nothing sooner...
thank you for the info and the studys...
sorry i dont reply sooner it takes me mad long to type and i feel like im brain dead with the TX lol i cant spell small azz words... other wise i m feeling good still.. i will keep u guys posted... had the ultrasound today results in 1 or 2 days
Great suggestions!
"I have had at least 12 uric acid kidney stones"
-----------------------
Have you been checked to see if you're insulin resistant?
Because uric acid is associated with insulin resistance....and many cirrhotics are insulin resistant.
(See my previous posts).
And if you do have IR.....improving insulin sensitivity (with diet, exercise, meds), can slow down the liver damage.
"Don't worry you can be on HCV treatment and have kidney stones. They are totally separate and do not interact in any way"
---------------------
They do if they're uric acid stones.
Co
"I have had at least 12 uric acid kidney stones"
-----------------------
Have you been checked to see if you're insulin resistant?
Because uric acid is associated with insulin resistance....and many cirrhotics are insulin resistant.
(See my previous posts).
And if you do have IR.....improving insulin sensitivity (with diet, exercise, meds), can slow down the liver damage.
"Don't worry you can be on HCV treatment and have kidney stones. They are totally separate and do not interact in any way"
---------------------
They do if they're uric acid stones.
Co
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