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Hispanic SVR Rates and Geno 3 Relapses
<a href="http://www.medicalnewstoday.com/medicalnews.php?newsid=55414">from Win-R</a>
-- Past studies with standard interferon plus ribavirin therapy suggest that ethnic origin may be an important predictor of response, with SVR rates highest in Asian patients (61%), followed by Caucasian (39%), Hispanic (23%), and African-American (14%) patients.(7) The WIN-R study included the largest dataset in Hispanic patients reported to date, and the results confirm that hepatitis C is challenging to treat in this population. Rates of SVR were significantly lower in Hispanic patients compared to Asian patients and Caucasian patients: 34% vs. 52% (p=0.0002) and 46% (p=0.0057), respectively. ....
-- Patients with HCV genotype 3 high viral load (Dr. Robert Brown and colleagues).(8) Patients with HCV genotype 2 or 3 (G2 or G3) generally respond better to treatment than patients with genotype 1,(9) and most studies have reported treatment responses in G2 and G3 patients as a single group. In WIN-R, these responses were examined separately, and showed that G2 patients achieved higher SVR rates (66% vs. 55%, p<0.0001) and lower relapse rates compared to G3 patients. G3 patients with high baseline viral load were more likely to relapse. While these findings suggest higher doses of ribavirin may benefit patients with hepatitis C additional research is needed ....
-- Past studies with standard interferon plus ribavirin therapy suggest that ethnic origin may be an important predictor of response, with SVR rates highest in Asian patients (61%), followed by Caucasian (39%), Hispanic (23%), and African-American (14%) patients.(7) The WIN-R study included the largest dataset in Hispanic patients reported to date, and the results confirm that hepatitis C is challenging to treat in this population. Rates of SVR were significantly lower in Hispanic patients compared to Asian patients and Caucasian patients: 34% vs. 52% (p=0.0002) and 46% (p=0.0057), respectively. ....
-- Patients with HCV genotype 3 high viral load (Dr. Robert Brown and colleagues).(8) Patients with HCV genotype 2 or 3 (G2 or G3) generally respond better to treatment than patients with genotype 1,(9) and most studies have reported treatment responses in G2 and G3 patients as a single group. In WIN-R, these responses were examined separately, and showed that G2 patients achieved higher SVR rates (66% vs. 55%, p<0.0001) and lower relapse rates compared to G3 patients. G3 patients with high baseline viral load were more likely to relapse. While these findings suggest higher doses of ribavirin may benefit patients with hepatitis C additional research is needed ....
Yeah -- can't blame you there. I hear Ross can really wear a girl out. Just getting in the front door can be a squeeze, then when you're done there's still that oversized sack to contend with...
I am the grandmother and mother every kid wants on christmas. I buy so many toys, the kids get bored opening them all! (The little ones) This year they are in for a surprise. I may get one gift, if lucky online. NO more Ross for me this year. Oh well, I was spoiling them anyway. Besides not working, I don't have the energy to shop more than a half hour.
Send me an email!
Send me an email!
Good looker? Maybe I used to be but on tx I look like the night of the living dead half the time. don't care either! Am I gonna see you when I'm in LA this week?
shall i send you a cryptic message? maybe just email you instead, ha ha! to bad you'll miss the Christmas Parade that's going on now (not) I can be a Scrooge sometimes...
ha, you shoulda shown that lady this, this will have REALLY confused her!!! Most of us are mutts anyway...this racial classification is pretty dubious at best...
The Caucasus historically were a fascination for Europeans. Prometheus and Jason and the Argonauts were myths featured in the Caucasus. Greek mythology considered women from the Caucasus to have magical powers.[3]
The reason the Caucasus had such an attraction to Blumenbach and other contemporaries was because of its proximity to Mount Ararat, which is the historical homeland of the Armenians where according to the Biblical account, Noah's Ark, eventually landed after the flood and the famed beauty of Caucasian women. Blumenbach believed that the original humans were light-skinned, that the Caucasians had retained this whiteness as a constant, and that darkness of skin was a sign of change from the original.[citation needed] The tribe of Japheth was supposed to have originated in the Caucasus, then spread north and westwards. Historically, the Russian borderlands of the Caucasus and Georgia were a source of sex slaves for Middle Eastern and Mediterranean peoples.[citation needed]
The beauty associated with these slave women from the Caucasus associated the word Caucasian with "enslaved embodiments of vulnerability" for Blumenbach. Blumenbach was enthralled by the beauty he claimed to see in exemplarary Georgian skulls, so he named his racial type after the famed beauty of the Caucasian peoples. After Blumenbach's time, the term Caucasian no longer was associated with peoples from the Caucasus but continued to be used as a racial indicator.[4]
Another 19th century anthropologist, Thomas Huxley, considered the scope of Caucasian to be inaccurate and "absurd", claiming darker Caucasians such as Southern Europeans & Middle Easterns were actually hybrids of light-skinned Northern European Caucasians and indigenous dark-skinned Australians.[5] The term Caucasoid (Caucasian-like) also came into use to encompass a larger grouping of populations with similar skull-shapes, including many North African, South Asian and Middle Eastern peoples.[citation needed] Carleton Coon did not use the term Caucasian and Caucasoid interchangeably. He used the term "Caucasian" or "caucasic" to reference the subrace of Caucasoids located around the Caucasus.[6]
[edit] Later uses of the term
Usage of the term Caucasian as a racial classification declined in Europe in the 19th century because it did not allow for enough distinctions as required by the new forms of nationalism that were emerging. In The United Kingdom, Caucasian refers to people from the Caucasus.[7] In Canada, the term Caucasian is known, but rarely used as a description of white people. In Australia and New Zealand, the term Caucasian is mainly used in police offender descriptions. In New Zealand, the terms more commonly used to describe white people are Pākehā, European New Zealander, or simply New Zealander (although in theory this should include all citizens or residents of the country).
[edit] United States
In the United States, Caucasian has primarily been used as a distinction based on skin color, for a group commonly referred to as White Americans, as defined by the government and Census Bureau.[8] A large segment of the Hispanic community in the United States can be scientifically categorized as Caucasoid, but may not be labelled as white (by themselves or others).
The Caucasus historically were a fascination for Europeans. Prometheus and Jason and the Argonauts were myths featured in the Caucasus. Greek mythology considered women from the Caucasus to have magical powers.[3]
The reason the Caucasus had such an attraction to Blumenbach and other contemporaries was because of its proximity to Mount Ararat, which is the historical homeland of the Armenians where according to the Biblical account, Noah's Ark, eventually landed after the flood and the famed beauty of Caucasian women. Blumenbach believed that the original humans were light-skinned, that the Caucasians had retained this whiteness as a constant, and that darkness of skin was a sign of change from the original.[citation needed] The tribe of Japheth was supposed to have originated in the Caucasus, then spread north and westwards. Historically, the Russian borderlands of the Caucasus and Georgia were a source of sex slaves for Middle Eastern and Mediterranean peoples.[citation needed]
The beauty associated with these slave women from the Caucasus associated the word Caucasian with "enslaved embodiments of vulnerability" for Blumenbach. Blumenbach was enthralled by the beauty he claimed to see in exemplarary Georgian skulls, so he named his racial type after the famed beauty of the Caucasian peoples. After Blumenbach's time, the term Caucasian no longer was associated with peoples from the Caucasus but continued to be used as a racial indicator.[4]
Another 19th century anthropologist, Thomas Huxley, considered the scope of Caucasian to be inaccurate and "absurd", claiming darker Caucasians such as Southern Europeans & Middle Easterns were actually hybrids of light-skinned Northern European Caucasians and indigenous dark-skinned Australians.[5] The term Caucasoid (Caucasian-like) also came into use to encompass a larger grouping of populations with similar skull-shapes, including many North African, South Asian and Middle Eastern peoples.[citation needed] Carleton Coon did not use the term Caucasian and Caucasoid interchangeably. He used the term "Caucasian" or "caucasic" to reference the subrace of Caucasoids located around the Caucasus.[6]
[edit] Later uses of the term
Usage of the term Caucasian as a racial classification declined in Europe in the 19th century because it did not allow for enough distinctions as required by the new forms of nationalism that were emerging. In The United Kingdom, Caucasian refers to people from the Caucasus.[7] In Canada, the term Caucasian is known, but rarely used as a description of white people. In Australia and New Zealand, the term Caucasian is mainly used in police offender descriptions. In New Zealand, the terms more commonly used to describe white people are Pākehā, European New Zealander, or simply New Zealander (although in theory this should include all citizens or residents of the country).
[edit] United States
In the United States, Caucasian has primarily been used as a distinction based on skin color, for a group commonly referred to as White Americans, as defined by the government and Census Bureau.[8] A large segment of the Hispanic community in the United States can be scientifically categorized as Caucasoid, but may not be labelled as white (by themselves or others).
half Mexican and half Swedish? me thinks you might be a looker! ha ha! Anyway, I know youre a very nice kid, that's all I know...
like running in a and out of a labyrinth, trying to figure all this stuff out...
like running in a and out of a labyrinth, trying to figure all this stuff out...
I am half mexican and half swedish, so who knows about my diet! Those beans on the BBQ don't work, so I have to eat those fatty foods with my riba. Wish I had that sx of weight loss...I guess I did when I used to eat the gallons of ice cream in the beginning and didn't gain weight. All bets are off now...
I'm gonna guess yes. Low body fat is a known positive predictor. Not a leap to guess that a low fat diet is a good thing. On tx, it seems the fat helps the riba absorbtion - so it's hard to go low-fat when your adding fat into your two biggest meals.
I've a funny story about "Caucasion". I was at the hospital waiting for the elevator to go visit my new grandson. No one was around except me. This Caucasion (Anglo-American) woman came down the hall just a grumblin' to herself as she looked at a piece of paper she was holding. She walked right up to me, showed me the paper (which was a birth certificate) and pointed to the box that said "Race" and said "What does this mean?" (it read "Cauc."). I told her it was Caucasion. Well, she was outraged and said "My babies ain't Caucasion! They're White!". I said that's what Caucasion means. She just looked at me with the dumbfounded look on her face and said "Oh" and went on her merry way. Very weird but funny experience.
yeah, it's interesting, but years of eating a low fat diet, thus, less fat cells and fat ratio prior to treatment> I do wonder about the low fat diet...if it's really the important factor prior to treatment? and what during treatment? interesting questions anyway...
I bet you are right and diet does has something to do with ability to clear the virus. Asians with their low fat diests do the best, ethnicities with higher fat diets do less well...interesting info.
Maybe the green tea consumption has something to do with it?
Maybe the green tea consumption has something to do with it?
he he he, any latinas out there, you know he's a goofball! guess I missed the memo on that "too busy taking care of their men" cultural convention, ha ha ha ha!
I think it's the beans and jalopenos. The beans off-gas the ribiviran and the jalopenos neutralize the interferon. Plus the latin chicks are too busy paying 'special attention' to the men in their lives and they forget to take their meds. That's what I hear on the 'foreign brides' forums anyway.
IIRC, the win-r was a long term study with 5000 participants. You can probably buy the full text on-line for 35 bucks or so. There's probably a wealth on informnation there for anyone interested in inferring odds of success based on age, gender, BMI, viral load, ethnicity, detailed sexual history.
That last one isn't covered in the study, but if you'll kindly just post the explicit details, many of us here will respond appropriately.
IIRC, the win-r was a long term study with 5000 participants. You can probably buy the full text on-line for 35 bucks or so. There's probably a wealth on informnation there for anyone interested in inferring odds of success based on age, gender, BMI, viral load, ethnicity, detailed sexual history.
That last one isn't covered in the study, but if you'll kindly just post the explicit details, many of us here will respond appropriately.
hey Goof, wonder if this is the study that 2irish was in? Anyway, I do think that cultural bias and socio-economic factors may be present, but who knows the ratio on that one? Wish we weren't in the dark and merely speculating on so many of these issues, including the experts...
do remember reading mortality rates among men in the US, with Japanese men living the longsest, then Hispanics, then Caucasian (that being such a questionable designation, I prefer to use Anglo-American or Anglo...it says Caucasian on my birth certificate, because I guess I was more light-skinned then my sister? While my sister has Latin-American? go figure, I think few whites(?) are decended from the Caucausus mountain regions) then African-Amercians....we can only speculate how much genetics plays into these studies, all the myriad factors to consider...compliance issues have to be factored in, which might have to do with cultural bias, etc...yikes, my brain could explode factoring all these negatives and positives...
forgot my manners, thanks for this!!!!
do remember reading mortality rates among men in the US, with Japanese men living the longsest, then Hispanics, then Caucasian (that being such a questionable designation, I prefer to use Anglo-American or Anglo...it says Caucasian on my birth certificate, because I guess I was more light-skinned then my sister? While my sister has Latin-American? go figure, I think few whites(?) are decended from the Caucausus mountain regions) then African-Amercians....we can only speculate how much genetics plays into these studies, all the myriad factors to consider...compliance issues have to be factored in, which might have to do with cultural bias, etc...yikes, my brain could explode factoring all these negatives and positives...
forgot my manners, thanks for this!!!!
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