Week 8 results just came back with WBC count for my husband at 2.8, is that low enough that it should be treated? He doesnt follow up with the doctor for another week, so I guess we'll find out then, but i thought maybe some of you would know the answer before that.
thanks & Happy Valentines Day everyone :)
My absolute Neutrophils (ANC) fell from 3.2 to 0.7
My doctor said that these counts looked stable, and to just continue my treatment as I have...and this was confirmed by the people in the know here.
My doctor told me she watches the ANC more closely then the WBC, and if ANC falls to .5 or below we will review the need for a rescue drug at that time. This also was confirmed by many here as the time to consider rescue drugs.
I take another blood test this Friday, so we will see where I am at at that time.
I do my interferon shot on Friday evening and have my cbc's run on Monday afternoon. They are consistantly at 0.2-0.3, so do the neupogen shot. On Thursday I had a second cbc run and the ANC would be at 0.7 or higher. Since I was seeing a hematologist that is affiliated with a cancer trt center, his threshold for neupogen was for an ANC at 1.0 or lower.
My point is, it really depends on what day you do the Inf shot and what day you have the cbc run. For me, the interferon hammers my wbc/anc and it goes very low 3-4 days later and rebounds later during the week, just in time for the next shot.
After reading many publications which clearly show no correlation between the ANC and risk of infection for HCV patients, I discussed stopping the Thursday nuep shot with my hemo and finally down to one per week. With cancer trt there is a high risk of infection with a low ANC and wbc, so I believe this threshold of trt has been transferred to HCV patients, at least in my personal experience.
Although a low WBC goes hand in hand with a low ANC, as others mentioned the docs pay closer attention to the ANC. It is actually a complicated calculation beyond my explanation that you can google to read more about if interested.
The WBC is different from the ANC count which is a part of the WBC.
You may have a 2.4 WBC and have an even lower ANC count.
What I think most doctors look at is the ANC count. Absolute Neutrophil
If another could comment please help us out with with this one.
My understanding of this might be a little off and I want to be sure of this...
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