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If the body produces Interferon on its own at what X times Factor are w...
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If the body produces Interferon on its own at what X times Factor are we injecting at 180?

Even though I have completed treatment I have wondered how did they come up with the proper dosage to overcome the virus and how many times above the bodies own production of Interferon, 1000, 10.000? I think I’m asking this question right.

jasper
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476246 tn?1418874514
Interesting question... I wonder if there are any answers out there
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577132 tn?1314270126
Very interesting question, I hope we hear some answers.  Sounds like an HR question, doesn't it, but we don't see him round these days...
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Avatar m tn
Me thinks the "big guys" know that answer...and only them.
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148588 tn?1465782409
"180" = 180 micrograms    .00018 gram

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2193578

One out of 1000 of your PBMCs are natural IFN alpha producing cells. An NIPC can produce 10 picograms of IFN alpha   .00000000001 gram when exposed to viruses or bacteria.
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Avatar n tn
hmm - I think this would be a hard thing to quantify. As pointed out in the above study a lot of cell types, not just immune cells, will express  various ifn a/b genes when RNA virus is detected and some of this is intended to diffuse to neighboring cells.

The average number of ifn molecules in the nucleus of   hepatocytes with/without tx might be a good indicator, but am not sure how one might measure that.
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148588 tn?1465782409
"...how did they come up with the proper dosage to overcome the virus..."

They haven't. Everyone is different - all they've come up with is the dosage that the average person can tolerate.
How'd they do that? Probably the way they usually do - trial and error
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