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1726450 tn?1316286111
Itching with no rash
Week 2. Incivek, RIBA, interferon.

Woke up itching like crazy, all over. My skin isn't dry, and I have no rash.

Don't want to take a benedryl.

I was finally in a deep sleep, and woke up in this itch state, very annoying.

Other than that, so far side effects have been tolerable.

Has anyone had itching without dry skin or rash, and if so- what did you use.

Thanks.
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11 Answers
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1669790 tn?1333666195
This is one of the most common sides from Incivek, so you should get plenty of suggestions from those that are dealing with the same thing.  You can do a search on this forum and see many posts talking about itching/rashes.  I'm on Inf/Riba and also have the same issues, so it may not be just the Incivek causing this issue.  

I've resorted to taking Claritin during the day, benedryl at night if I have a flare up.  Also, hydrocortisone cremes help to calm the itch.  I've tried many of the creams and lotions, and nothing else seemed to help.   Try not to wait until the itch gets to the point of interfering with sleep or becomes unbearable.   See a dermatologist to get it under control before that point if you can.  

Also, try to avoid the heat/sun/sweating, hot showers, rubbing, scratching, since this will only make it worse.  Scratching an itch is one of life's simple pleasures, but not in this case.

Hope it calms down for you.
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I had itching and some signs of rash and I take the same treatment on week 2 now, took second shot Friday. The rash isn't visible but I can feel some bumps behind my knees and on other sensitive areas of skin and here is how I am managing it:

Aveeno body wash - a little expensive but god it helps
Aveeno lotion - works great
Non-Drowsy anihitamine during the day - Claritin, Zyrtec, Alegra
Benadryl at night - this not onlyhelps the itching but helps you sleep through it as well
Lot's of water to keep you hydrated

Aveeno is made with oatmeal and you can use it to wash or just soak in and it will help then use the lotion. Try this it will help!
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PS

Don't use any detergents or lotions with lots of perfume it will only irritate your skin more. Do not use any body sprays or perfumes/colognes. If your underarms are sensitive get a deoderant that is hypoallergenic. You can also get plain oatmeal and blend it to a powder in your blender then put it in a warm bath it will ease the itching. Unfortunately even beforfe the treatment I've always had sensitive skin so I've used these methods many times they will work!
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1658980 tn?1330715150
If the OTC remedies do not work or make it worse (happened to me), ask your doc for a referral to a dermatologist- hopefully you can find one that is familiar with this tx and its side effects.  I was so lucky to have one that works with my doctor.
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PSS

The benadryl should be taken 30 minutes before bed. For daytime, or if you just do not want to take benadryl look for any antihistamine that does NOT contain dyphenhydramine, that is the main ingredient for benadryl.
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You can also try to find lotions that contain hydrocortisone they will help
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I keep a 1% cortisone creme with me at all times. It sleeps with me and when I feel an itch I use it.Strange itch it moves around a lot and not always a rash. Very annoying , especially as treatment goes on and you become more irritable. Or is it just me who is becoming more irritable?????
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1726450 tn?1316286111
Thanks everyone, I will look into the anti itch cream.

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You are not alone! I to have noticed that one minute it may be my shoulder itching and as soon as I scratch that it becomes an itch on my leg! It is EXTREMELY frustrating and I to get very irritable over it. There are even times that if I scratch the itch just gets worse not better, that's about the point I want to start scratching with a pitch fork and cursing all at once!  Instead I try to focus on something else or take a bath...needless to say I'm very clean!
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1833444 tn?1325560662
I have no rash just the itching, I'm all the pegas+ribia+incevik like you woke up one day and the itching was unbearable espiecally on the inside of the inner thighs and arm. I did not want to take any more drugs than I have to but had to do it I just couldn't take the itching any more and broke down and took the Benadryl (per my pharmacist) it works and I take just one every couple of day...seems to work for me, hope you can fine what works for you.Good luck
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665963 tn?1360727154
I always use coconut oil after my shower. I don't want the dry skin to even start.  For itching I've used benedryl to help sleep, extra strength gold bond is good.  If that doesn't help, I have a 2.5% hydrocortosone cream.  Also, an ice pack can help curb the urge to scratch.
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