Aa
Lambda study update
Had my twelve week bloods drawn last Fri and just found out that I am UND. Just wanted to share the positive (negative) news - beyond that I am still speechless.
Susan
Susan
I admit that having so few symptoms I feared that the treatment wasn't working. Sure am glad that I was wrong.
Your information is exciting. Do you know if Bristol-Myers new drugs would eliminate the Riba portion of tx? If I were recently diagnosed and able to wait 5 to 10 years then I would probably do just that. That the Lambda currently looks to be effective against all genotypes with 24 weeks of treatment is super. That the aim is to reduce that to 12 weeks for G2 & 3 is really inspiring. A vaccine would, of course, be nirvana.
Being a newbie to Hep C I bought shares of Vertex a few years back because my then doc was in charge of the studies. Somehow I thought this would help in some way... Although I realize now how naive that was, I still hold the shares and heard just today that the Telaprevir has been shown to be very effective in those who are co-infected with HIV. Somehow, there seems to be sufficient incentive to keep the pharm companies researching for the best approach to a cure. That kind of let's me know just how many people are infected.
I am ready for the day when everyone is clear!
Your information is exciting. Do you know if Bristol-Myers new drugs would eliminate the Riba portion of tx? If I were recently diagnosed and able to wait 5 to 10 years then I would probably do just that. That the Lambda currently looks to be effective against all genotypes with 24 weeks of treatment is super. That the aim is to reduce that to 12 weeks for G2 & 3 is really inspiring. A vaccine would, of course, be nirvana.
Being a newbie to Hep C I bought shares of Vertex a few years back because my then doc was in charge of the studies. Somehow I thought this would help in some way... Although I realize now how naive that was, I still hold the shares and heard just today that the Telaprevir has been shown to be very effective in those who are co-infected with HIV. Somehow, there seems to be sufficient incentive to keep the pharm companies researching for the best approach to a cure. That kind of let's me know just how many people are infected.
I am ready for the day when everyone is clear!
I have heard the goal is to be able to combine the new drugs Bristol-Myers is working on with the Interferon Lambda to create a cocktail that will reduce treatment time significantly along with making the treatment very tolerable. They are talking 24 weeks for G1 & 4 and 12 weeks for G2 & 3 with very few side effects. I have also heard they will be starting a study in the next few months with this new cocktail of drugs. This was the main reason for Bristol-Myers buyout of Zymogenetics the original developer of Lambda. This could change the whole landscape of treating Hep C and basically make a monopoly for Bristol-Myers. When come right down to it, it’s all about the money for the drug companies. There next step will be to produce a vaccine for Hep C. My experience with Lambda has been unbelievable. Very few sx during treatment, none that stopped me from any part of my normal life, the lowest my HGB dropped to was 13.8. No sx after treatment. 3 month post treatment and still UND. I have been a member of this forum since July 2010 and have read the posts of the members that are in treatment or have treated and feel very sorry for the sx they are experiencing. It makes me feel guilty that I had so easy. I am glad for you Susan. The end is near.
congratulations susan, wonderful news and good to hear you are not suffering too much from tx.
- Dave
- Dave
That is truly great news - all these new drugs are really changing the landscape but either way getting to UND is fantastic spectacular marvelous news and you deserve it!
Susan Congrulations and God Bless you. Very Proud of yourself for being strong and hanging in there with the treatment. So happy for you. God Bless you.
This is great news and you are getting closer to the end. Wow, Hep C free has a nice ring to it. I'm sure this brings that light at the end of the tunnel a little closer.
Spring is coming too, I wish you continued success and a hep c free life.
Spring is coming too, I wish you continued success and a hep c free life.
Robert, as I understand it the lambda is specific to hepatocyte cells and, therefore less of the body is under attack. (My words.) They do know that there are fewer of the hematological se's associated w/ alpha. (Only 1 person has had to drop out because of this.) My own blood counts have stayed well within range. Also, there are fewer flu-like symptoms. (I haven't had any.) What I do attribute to the lambda is some low level nausea and some tiredness about 24 hours after the injection. Some loss of concentration. All in all it's been an easily tolerated therapy.
BTW, for any who might be interested I know that they are still recruiting at the clinic I attend (Duke in Durham, NC.) This arm is specific to treatment naive 1a's with the CC allele.
BTW, for any who might be interested I know that they are still recruiting at the clinic I attend (Duke in Durham, NC.) This arm is specific to treatment naive 1a's with the CC allele.
Grats Susan. How are the sides with the lambda IFN compared to the alfa IFN's?
Robert
Robert
Thank you all for the well wishes and kind words - they mean a lot. I wish that everyone achieve UND and then SVR. And a big thanks to the dedicated researchers...
My study nurse keeps reporting that everyone in the lambda studies is maintaining UND!!! I can't believe that I've been so fortunate in having minimum sides and slated for only a 24 week run of meds. All this while not changing my normal supplements - including fiber and milk thistle, and haven't restricted my diet in anyway at all. This is progress I can love.
I've cried with joy any number of times today and next, I plan on tearing up when I hear your good results.
S
P.S. Cabbages are beautiful ;).
S
P.S. Cabbages are beautiful ;).
Congratulations. Your on your way. I just got my 3 month post treatment results. I am still UND. Maybe Lambda is the real deal. I sure hope so! We are so fortunate to be in this study.
I HAD to look! Congratulations. I feel like crying ! This is great news. How's that cabbage you jiggy thing? YES!
K
K
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