Legs- Swollen

My sister is 4th stage liver disease. She has to give herself
three shots a week....I don't know what all of her medicines are
except that ONE of them is Inerferon.

Recently,  she developed these large rashes on her thighs. The rashes are becoming somewhat like welts now. They are hot to the touch,  and are hard underneath. And now her legs are so swollen she can't bear to stand or walk.

  She's called her doctor who simply told her,  "Well, just hang in there UNLESS you start having a fever, OR if the rashes become hardened."  Once the rashes got hard, she began calling her doctor back but couldn't get a return call. Now the doctor just tells her to contact her Primary Physician.

  I am afraid for her! Does anybody know what these hardening rashes and swelling might be caused by? Is she in danger (It sure SOUNDS like it to ME.) or is this something that is just supposes to be waited out?

THANKS, Everyone for so much help and support! Jackie