We often discuss the diagnostic value of biopsy in regards to Stage and Grade in estimating fibrosis, but a good liver biopsy reviewed screened and reviewed by an expert pathologist can provide essential and valuable information. A good reminder to everyone why it's important to get copies of all your lab reports.
Title: Liver Biopsies in Chronic Viral Hepatitis Beyond Grading and Staging
Author: Hudacko, R / Add.Author / Editor: Theise, N
Citation: ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE 135 (10): 1320-1328 OCT 2011
"Abstract: Context.-Knowledge of the etiology and pathogenesis of chronic viral hepatitis has grown immensely during the past 50 years. The terminology used to assess liver biopsies with chronic viral hepatitis and the role of the liver biopsy itself have also evolved during this time. Although the focus of much discussion regarding diagnostic assessment of liver biopsies in patients with viral hepatitis has been on grading of activity and staging of fibrosis, each biopsy is also an opportunity to assess many other important features.
Objectives.-To discuss opportunities provided by biopsies to assess features such as the presence of virus-associated premalignant or malignancy-related changes, and the presence of other concomitant diseases, including fatty liver disease of diverse causes, and hemochromatosis, hereditary or otherwise.
Data Sources.-The data were obtained from published literature and professional experience.
Conclusions.-The evaluation of liver biopsies with chronic viral hepatitis has evolved beyond grading and staging. Pathologists need to be aware of the other features that may have important clinical implications. "
* For the hardcore people who want to understand liver biopsy from the clinician's point of view. The AASLD position paper "Liver Biopsy" published in HEPATOLOGY, Vol. 49, No. 3, 2009 is an A-Z summary of the current practice of liver biopsy.
Oh boy. I'm planning on seeing my gastro next month to ask him about having another bx since it's been over 10 years since my last. He already thinks I ask too many questions. If he finds out I favorited this to study, he'll tell me I don't need one.
This site complies with the HONcode standard for trustworthy health information.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.