Loss of Skin Pigmentation

[Lary__0]

  I have continually said I have no apparent symptoms related to my HCV. However, since being diagnosed 2 months ago, I have noticed quickly spreading patches of pigment loss especially on my back, shoulders, and chest. I'm in early stage cirrhosis, any correlation?

[HFHSM.D.-D.M.]

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Dear Larry:
I was very intrigued by your question.  It is theoretically possible that your loss of pigment may be related to your hepatitis C.  Some individuals who have loss of pigment have a condition called vitiligo.  Vitiligo may be an autoimmnue condition and there is some evidence that people with hepatitis C are more predisposed to autoimmune conditions.  When I looked at the literature, I found one report of an individual with hepatitis C who also had vitiligo.  This actually isn’t a lot given that both conditions are relatively common.  I do know that loss of skin pigmentation has been associated with interferon therapy for hepatitis C though you do not mention that you are receiving treatment.  
I hope this information is helpful to you.  Good luck with your situation.  If you have additional information or questions, I would invite you to post the material to MEDHELP or to contact us directly at Henry Ford [phone]. We have an active group of liver specialists and we have a strong interest in and experience with hepatitis C and liver transplant.
This response is being provided for general informational purposes only and should not be considered medical advice or consultation.  Always check with your personal physician when you have a question pertaining to your health.