Pain after tx

[Jerbobs]

wondering long term side effects of Pegasys and ribovaviran?

[JasmineT]

You may want to try taking some vitaminb12
http://www.livestrong.com/article/549510-b-12-for-lymph-nodes/

After treatment, when I have researched my various nuisance issues, b12 has come up consistently.  Along with a little NADH(b3), d3, and e.  I started adding vitamins to my days and felt much better.

My blood work did not show a b12 deficiency but it still seems to help.

Hope you feel better soon.

[Advocate1955]

My husband had to stop therapy in mid April 2012, due to a viral breakthrough.  He was on triple tx with Incivek, and it was his third time tx'ing, Each of which failed. He does not have any long term effects from any of his three txs.  Each time it has taken him about 8 weeks after ending txs to feel better.  What I have noticed is the general increase in fatigue over the years as the Hep C continues to cause liver damage.  His Hep C was diagnosed in 2007, and he now has Cirrhosis, which was diagnosed in 2010.
Advocate1955

[bamabred]

Hey buddy,if you find out about studys on long term affects please let me know please,im or ***@****,thanks. Ill do the same. :)

[Jerbobs]

That was 11 years ago. Post interferon syndrome.  There has been no recourse that i can take. Some patients have no long lasting side effects while some have a long list of comorbidities that will lead to their decline.  
Statue of limitations for negligence approved by Congress and states governors.  
Instead of resentments i developed because of this toward people ive decided to not let the past control me.
It doesnt define me as a person. Buddha  said
Anger is like a present. If the person you have anger toward doesn't accept it what do you have ? Anger

[Jerbobs]

thanks

[orphanedhawk]

Thanks for replying. Although I don't know whether this is from hep C tx or not, someone more knowledgeable than I, may have some better answers for you about your painful lymph nodes.

[Jerbobs]

I completed tx a little more than ayear ago successsfuly. Every test taken has come back normal. I have unexplained painful lymphnodes in my right groin and joints and muscle aches. rheumitoligist thinks its chronic pain syndrome i think its bs . THanks for any input you have

[rambleon40]

It also seems that most recent journal articles discussing triple combination therapy are addressing the new or enhanced adverse effects of the therapy (anemia, rash, anal problems) - they are not discussing at any length or at all the long-recognized effects from IFN alone or IFN - Ribavirin therapy.  

See, e.g.  http://www.gastrojournal.org/article/S0016-5085(12)00225-9/fulltext

[rambleon40]

One has to question whether the research is complete, accurate and / or fully disclosed.  

Much of the research down on the IFN combo therapies has been done by clinicians who are paid by Merck, Roche, Pfizer, etc.  

Recognizing that such conflicts of interest can influence results, most journals now require disclosures of conflicts of interest.  

See,

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735425/

for one of many discussions of this issue.

The extensive literature on this issue references med journal "infomercials," data manipulation, incomplete data, improper payments, etc.  Many of our doctors get their info from sources subject to these problems - they run to Medline and look things up and have no knowledge of who the authors are or who paid them.

If anyone knows of a study where the long-term side effects of treatment have been quantified and qualified with or without the unfortunate yet almost inevitable bias of clinicians' financial self-interest, I would certainly appreciate a link to it.

[FaithforHealing]

I had to have my inf reduced after week 12 and within 7-10 days I started feeling better. My tx team tells me most people recover quickly after tx. But as others have said, everyone is different. I think if the majority of people do fine or we would be hearing more about it in terms of research and it would weigh more heavily in doctors advising patients to treat or not to treat.

[slideman]

I took my last int shot Dec 19th 2011, and have absolutely no sides that I can say definitely came from tx.

[orphanedhawk]

It might help us to more fully reply to your question if we knew more about you.
How long ago did you finish treatment and where is the pain you mention?

[stormy456]

Good response, Idyllic.  Jerbobs - I think the answer varies wildly, with some people having serious challenges post-tx, and some having none.  My husband is now 10 weeks post-tx and has absolutely no lingering side effect, except of course for the hair loss, which he is hoping stops and reverses very soon.

[Idyllic]

Sorry no one is responding to your post. Yours is a frequently asked question. Here are a few related posts:

This one has a lot of comments:
http://www.medhelp.org/posts/Hepatitis-C/Side-effects-of-peginterferon-alfa-2a-pegasys-and-ribavirin/show/87872

http://www.medhelp.org/posts/Hepatitis-C/Long-term-effects-of-Pegasys-Ribavirin/show/1134324

http://www.medhelp.org/posts/Hepatitis-C/Long-term-after-effects-of-tx-w-Pegasys-or-PegIntron/show/96929

http://www.medhelp.org/posts/Hepatitis-C/5-years-after-Pegasys-interferon-ribavirin-treatment/show/623653

http://www.medhelp.org/posts/Hepatitis-C/long-term-after-effects-post-interferon/show/89426