Aa
A
A
Close
Avatar_universal
Phase I Study New Hep C Drug for Peg/RBV Nonresponders
Anyone interested in joining a study for the evaluation of a new drug....pls read details below:
Cancel
7 Answers
Page 1 of 1
Avatar_universal
Phase I Study New Hep C Drug for Peg/RBV Nonresponders

Peregrine Pharmaceuticals' anti-viral Phase 1 trial is designed to evaluate the safety of escalating doses of Tarvacin in patients with chronic Hepatitis C virus infection.

Below is a summary of the trial parameters:

Tarvacin is a monoclonal antibody designed for solid-tumor cancers.
http://www.tarvacin.com

Protocol Title:
A Phase I Study of Chimeric Anti-Phosphatidylserine Monoclonal Antibody (Tarvacin™) in Patients Chronically Infected with Hepatitis C Virus (HCV) who are Non-responders or Relapsers after Treatment with Pegylated Interferon plus Ribavirin

Contact Information
Karen Roberts, MS      714.508.6035    ***@****

PHASE I STUDY SITE  
Bach & Godofsky, MD, PA, Bradenton,  Florida,  34205,  United States; Recruiting
Mickey Mays, RNMS, ARNP  941-746-2711  Ext. 39
Eliot W Godofsky, MD,  Principal Investigator

Phase: I
Indications: Chronic Hepatitis C virus (HCV) Infection

Objectives:
--Determine safety and tolerability
--Characterize blood pharmacokinetics and viral kinetics
--Define the maximum tolerated dose (MTD) and/or maximum effective dose (MED)

Selected Eligibility Criteria:
    
Inclusion
--Must be 18 years of age
--Chronic HCV infection based on medical history and detectable serum HCV RNA

--Failure to respond to or relapse after treatment with pegylated interferon plus ribavirin

Exclusion
--No prior exposure to any chimeric antibody
--No decompensated clinical liver disease or cirrhosis or other cause of liver disease such as alcoholic liver disease
--No uncontrolled intercurrent disease
--No requirement for chronic daily treatment with NSAIDs, anti-platelet drugs or steroids
--Must not be pregnant or nursing
--No prior thrombotic or hemorrhagic disorders



--------------------------------------------------------------------------------


_______________________________________________
NATAP nataphcv mailing list -- ***@****

Comment
Cancel
Avatar_universal
Comment
Comment
Submit Comment
Avatar_universal
thanks for the details, Ben. Someone gave us a preview on an 8/8 thread, I wonder if they got their 30 subjects by now? I think it was mentioned that they were looking for 30 individuals, or did I imagine that one?
Comment
Cancel
Avatar_universal
Comment
Comment
Submit Comment
Avatar_universal
Get tested for hepatitis C



--------------------------------------------------------------------------------
Otros Titulares
  Som
Comment
Cancel
Avatar_universal
Comment
Comment
Submit Comment
Avatar_universal
is that the LOLA article?
Cin
Comment
Cancel
Avatar_universal
Comment
Comment
Submit Comment
Avatar_universal

Affirmative!
Comment
Cancel
Avatar_universal
Comment
Comment
Submit Comment
Avatar_universal
Thanks!
Cin
Comment
Cancel
Avatar_universal
Comment
Comment
Submit Comment
Avatar_universal

You very welcome...
Comment
Cancel
Avatar_universal
Comment
Comment
Submit Comment
Your Answer
Avatar_universal
Answer
Know how to answer? Tap here to leave your answer...
Answer
Phase I Study New Hep C Drug for Peg/RBV Nonresponders
Submit Answer
A
A
Recent Activity
Avatar_universal
Blank
susan400 Just diagnosed w/Graves..st... Comment
2 hrs ago
4059843_tn?1454481984
Blank
mishymoshymarcy commented on need a title -
18 hrs ago
134578_tn?1446090952
Blank
AnnieBrooke commented on need a title -
18 hrs ago
Blank
Weight Tracker
Track your weight over time
Start Tracking Now
Top Hepatitis Answerers
446474_tn?1446351282
Blank
San Francisco, CA
1815939_tn?1377995399
Blank
317787_tn?1428318779
Blank
DC
Avatar_universal
Blank
163305_tn?1333672171
Blank
Rural Mural, CA
683231_tn?1438659664
Blank
Auburn, WA
Hepatitis C Community Resources