Aa
Please Answer
Dear All,
Exposure: unprotected vaginal sex
Testing: at week 23, Antibodies for HCV, negative.
Conclusive ?
Exposure: unprotected vaginal sex
Testing: at week 23, Antibodies for HCV, negative.
Conclusive ?
If you do not have HIV then it would not have the effect of delaying seroconversion so yes you would only need to be concerned about delayed seroconversion if you have HIV.
I would think that should be obvious that something you don't have cannot effect the HCV test result
I would think that should be obvious that something you don't have cannot effect the HCV test result
to repeat the last line
Where there is a clinical suspicion of recent HCV infection, for example, elevated alanine transaminase levels, HIV-infected patients should be screened for HCV RNA by RT–PCR.
However HCV is not generally considered to be an STD as it requires blood to blood contact and sexual transmission is relativly rare especially in the setting of long term monogamous couples.
My suggestion is if you tend to have worries about illness from unprotected sex
Then DON'T HAVE UNPROTECTED SEX then no worries.
My personal belief is it is highly unlikely you have hep C if you are still concerned you can have the HCV RNA by RT-PCR test done which I believe can be done in the US for around $200 to $300
Where there is a clinical suspicion of recent HCV infection, for example, elevated alanine transaminase levels, HIV-infected patients should be screened for HCV RNA by RT–PCR.
However HCV is not generally considered to be an STD as it requires blood to blood contact and sexual transmission is relativly rare especially in the setting of long term monogamous couples.
My suggestion is if you tend to have worries about illness from unprotected sex
Then DON'T HAVE UNPROTECTED SEX then no worries.
My personal belief is it is highly unlikely you have hep C if you are still concerned you can have the HCV RNA by RT-PCR test done which I believe can be done in the US for around $200 to $300
Delayed anti-HCV antibody response in HIV-positive men acutely infected with HCV
Abstract.Objective:
An epidemic of acute hepatitis C virus (HCV) infection among HIV-positive men who have sex with men is occurring in urban centers in Western Europe and the United States. Early diagnosis and treatment of HCV results in improved sustained virological response rates. This study compared the sensitivity of reverse transcriptase PCR (RT–PCR) versus antibody screening for the diagnosis of early HCV infection in HIV-positive patients and estimated the length of time from HCV infection to the development of anti-HCV antibodies.
Design:
Patients from the St Mary's Acute Hepatitis C Cohort (SMACC) were recruited retrospectively and prospectively between 2004 and 2008.
Methods:
Archived plasma samples, obtained at 1–3 monthly intervals for routine monitoring of HIV viral load were assayed retrospectively for HCV in order to assess the sensitivity of RT–PCR and enzyme-linked immunosorbent assay (ELISA).
Results:
Forty-three HIV-positive patients with early HCV infection were identified. The median CD4 cell count was 570 cells/μl. The median alanine transaminase at the time of the first positive HCV PCR was 65 IU/ml. At this time, 75% of patients had a negative HCV antibody test. Three months later, 37% of patients still had a negative result. After 9 months, 10% of patients had a negative test and 5% remained negative after 1 year.
Conclusion/discussion:
Delayed seroconversion in HIV-positive individuals with acute HCV may result in delayed diagnosis and treatment. Where there is a clinical suspicion of recent HCV infection, for example, elevated alanine transaminase levels, HIV-infected patients should be screened for HCV RNA by RT–PCR.
Abstract.Objective:
An epidemic of acute hepatitis C virus (HCV) infection among HIV-positive men who have sex with men is occurring in urban centers in Western Europe and the United States. Early diagnosis and treatment of HCV results in improved sustained virological response rates. This study compared the sensitivity of reverse transcriptase PCR (RT–PCR) versus antibody screening for the diagnosis of early HCV infection in HIV-positive patients and estimated the length of time from HCV infection to the development of anti-HCV antibodies.
Design:
Patients from the St Mary's Acute Hepatitis C Cohort (SMACC) were recruited retrospectively and prospectively between 2004 and 2008.
Methods:
Archived plasma samples, obtained at 1–3 monthly intervals for routine monitoring of HIV viral load were assayed retrospectively for HCV in order to assess the sensitivity of RT–PCR and enzyme-linked immunosorbent assay (ELISA).
Results:
Forty-three HIV-positive patients with early HCV infection were identified. The median CD4 cell count was 570 cells/μl. The median alanine transaminase at the time of the first positive HCV PCR was 65 IU/ml. At this time, 75% of patients had a negative HCV antibody test. Three months later, 37% of patients still had a negative result. After 9 months, 10% of patients had a negative test and 5% remained negative after 1 year.
Conclusion/discussion:
Delayed seroconversion in HIV-positive individuals with acute HCV may result in delayed diagnosis and treatment. Where there is a clinical suspicion of recent HCV infection, for example, elevated alanine transaminase levels, HIV-infected patients should be screened for HCV RNA by RT–PCR.
I tested for HIV, after 15 weeks and the result is negative
But I am concerned if i received HIV and HCV from my exposure that it will affect the testing of both viruses and I will get false negative results for both of them
But I am concerned if i received HIV and HCV from my exposure that it will affect the testing of both viruses and I will get false negative results for both of them
thank you very much
Should I concern about HIV/HCV coinfection and delayed seroconversion
?
Should I concern about HIV/HCV coinfection and delayed seroconversion
?
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