Aa
Aa
A
A
A
Close
Avatar universal

Reliability of blood products donor testing

I donated plasma twice last year, and on the second instance I was told that I had tested positive for the Hep C antibody, but negative for the reactive test. I scheduled a doctor's appointment and had a second test performed, which came up negative for both the Hep C antibody and the RNA test.

My question is about the accuracy of the screening tests performed on each blood product donation: I had unprotected sex with someone of unknown status (albeit low-risk, she was a friend) a few times about 9 months before these blood product donations occurred. Would that have been sufficient time for antibodies for viral diseases, such as Hep C and HIV, to appear in my bloodstream and be registered accurately by the screening test?

Thanks in advance for your help.
2 Responses
Sort by: Helpful Oldest Newest
683231 tn?1467323017
Antibody tests can have "false" positives under certain circumstances. Antibodies to hep c can take up to 6 months to develop if you immune system is compromised. Generally if you test positive for hep c antibodies you will test positive for life.

I am not a biological chemist and cannot speak to the relative accuracy of differing methods of the HCV antibody screening test. Really it is a moot point as you do not have hep c.

Antibodies are not the hep c virus they are made by your body in response to the hep c virus when it tried to fight off infection.

In general hep c is not considered to be an STD although that generally applies to those in long term monogamous relationships. For those who engage in rough sexual practices, have multiple sex partners or in the presence of HIV infection the risk is higher and safe sex practices like condoms and other barrier protections should be utilized.

The bottom line as evidenced by your HCV RNA test you do not have hep c. The HCV RNA test is the definitive for determination of active hep c infection.
Helpful - 1
18601474 tn?1466188088
Glad to hear of your negative results.

Here is some more information about how Hep C is transmitted that may help you understand this condition better in the future!

http://www.medhelp.org/hepatitis-c/articles/What-Is-Hepatitis-C/2251
Helpful - 0
Have an Answer?

You are reading content posted in the Hepatitis C Community

Top Hepatitis Answerers
317787 tn?1473358451
DC
683231 tn?1467323017
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.