Ribavirin and krill oil

I planning to take my morning ribavirin with my breakfast with a chunk of cheese. I am also taking krill oil, which one is supposed to take with the first meal.

My question is if it is okay to take either krill oil or fish oil at the same time as the riba?


Marcia

[mremeet]

I don't see why not. I've never heard that fish oil interferes with riba absorption or is otherwise contraindicated. Just make sure you get enough fat, I doubt if a few fish oil pills would be enough if that's all your taking. A chunk of cheese sounds perfect though.

[jmjm530]

A chunk of cheese sounds perfect though
-----------------------
Yes, and smear it with peanut butter to "take it up a notch".

[gauf]

Chase it with a chocolate malt.

[bandman54]

I think that is fine BUT,
watch the cheese... a person that eats a lot of cheese runs the risk of having a high uric acid level which can result in gout.  ouch!  Happened to me and it was no fun!

Plus a high uric acid level is a good indicator of tx failure.

Also, sardines, pickled herring can also contribute to high uric acid.

good luck!
It has not been near as bad as I had anticipated... although I feel like **** today!

bandman

[nygirl7]

peanut butters always a good way to get a good natural fat - or if you start getting nauseaus try some yogurt smoothies.  You'll be SO SICK of cheese by the time a month goes by...at least with the smoothies I could switch up the flavors a bit....that helped me a lot.

And don't forget our favorite standby - ice cream!

[jdwithhcv]

Avocado is also good, tasty too!

[bandman54]

Avocado is great!

actually the pills never have made me sick.  But the shot I take on Friday night, makes me nauseous on Monday.

I wouldn't get carried away on the peanut butter either.  Peanuts contain a high level of Vitamin E,... some studies have shown that Vitamin E encourages virus replication.

If you are taking a multi-vitamin, try to find one with the lowest vitamin E.

bandman

[Bill1954]

I’ve taken 3000mg/day omega-3 fish oil capsules for years now.

I also relapsed last treatment.

Hmmm :o).

[Marcia2202]

Thanks so much... You guys are so so funny...

Thanks for all the tips!

So krill oil and fish oil DON'T interfere with Riba absorption!

Great! So I can gulp it down with the raw French cheese a nice slice of Danish ryebread and I'll take a spoonful of VCO. Virgin Coconut Oil, that is. and the krill oil.

Marcia

Not into peanut butter nor ice cream. But avocado I like.

[jdwithhcv]

Sometimes I make a balsamic vinagrette dressing with olive oil and toss in crumbled Danish bleu cheese.  That's nice spread on the crisp rye bread.
jd

[Marcia2202]

Cheese is the only animal protein I'm getting. I usually only have some in the morning. I'm vegetarian, so no sardines and stuff.

I'm glad to hear it's bearable for you. Hope it stays like that.

I'm too excited... 13 more hours to my appointment. I can't wait to go to sleep and to wake up tomorrow morning... and go to the hospital...

Who would have ever thought that one could get so excited about going to see a doctor. This disease makes you go coocoo....  Aliens.... ;.)

[comeagain]

I dont  think thats coo coo, sounds like you very eager to go separate that dragons head from his shoulders.
Thats the spirit- , very inspiring to the rest of us,  good luck tomorrow.

ca

[Isobella]

jd:  Yummy!  That is the 2nd time in 2 days I read that recipe.  Sounds delicious-that's
      what I am  going to eat next pill time :-)

Marcia:  Yay for tomorrow!  If we all go to sleep now-tomorrow will be here sooner!!  I
             cannot wait to hear how it goes.  Don''t forget to drink plenty of water....
              then drink more!  

Go BADSS!!!

Isobella

[Marcia2202]

YAY!!!

JD... I love blue cheese... the Roquefort from Papillon is the bomb!!!

Thanks... Izzy and CA

Love you all....

Am going to sleep now....

11 1/2 hrs to go...... YAY

Marcia

[Rockerforlife]

Take your riba with some good whale blubber.

[Rockerforlife]

Krill are tiny shrimplike creatures that are at the bottom of the food chain, and, thus, don’t concentrate mercury in the same way that fish do. And krill have a unique phospholipid structure to their fatty acid bonds that makes them much more absorbable, preventing the fishy smelling belching that fish oil capsules sometimes cause. If you want to get your omega-3s as tastelessly and painlessly as possible - and without the risk of mercury toxicity - you can’t go wrong with krill oil.  http://www.proteinpower.com/drmike/supplements/another-reason-to-opt-for-krill-oil/

[bandman54]

Marcia,

I know that you know that you need a certain amt. of protein per day. If you do not get enough protein you WILL feel sick.

If you are only getting it from cheese, please have them check your uric acid level at each blood work.

I recommend a protein drink powder.

here is a protein calculator:
http://www.healthcalculators.org/calculators/protein.asp

Here is vitamin E study (watch the peanuts and multi vitamin):
http://aac.asm.org/cgi/content/full/51/6/2016?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&searchid=1&FIRSTINDEX=0&minscore=4000&resourcetype=HW


Here is uric acid info (don't worry if you do have high uric they will rx meds to bring it down:
Is serum uric acid a predictive factor of response to IFN-treatment in patients with chronic hepatitis C infection?

Pellicano R, Puglisi G, Ciancio A, Balzola F, Saracco G, Ciccone G, Baldi I, Abate ML, Smedile A, Rizzetto M. Department of Gastro-Hepatology, San Giovanni Battista (Molinette) Hospital, Torino, Italy.

Several factors, including metabolic profile, are predictive of response to standard antiviral therapy in patients with chronic hepatitis C. In a retrospective study, it was investigated whether uric acid, involved in metabolic syndrome, could be included. A total of 153 patients (56.2% males; mean age 45.7 +/- 11.3 years) treated with pegylated-interferon and ribavirin were included. Eighty-five were infected with hepatitis C virus (HCV) genotype 1 or 4 and 68 with genotype 2 or 3. Viral load was >1,000,000 IU/ml in 101, </=1,000,000 IU/ml in 35 and unknown in 17 patients. Ishak fibrosis score was 4 in 15 and unknown in 57 patients. Mean serum uric acid was 5.05 +/- 1.3 mg/dl. Sustained virological response (negative serum HCV-RNA 6 months after treatment cessation) was achieved in 102 patients (67%). In the final logistic model, serum uric acid level >/=5.8 mg/dl (OR = 0.46; 95% CI: 0.30-0.62), viral load (OR = 0.29; 95% CI: 0.09-0.92) and HCV genotype (OR = 0.23; 95% CI: 0.09-0.60) were identified as the most important factors independently influencing clinical outcome. The prognostic role of serum uric acid was confirmed on the sub-sample reporting Ishak fibrosis score (OR = 0.49; 95% CI: 0.28-0.85). Serum uric acid level >/=5.8 mg/dl is predictive of poor response to HCV treatment. Prospective studies are needed to clarify the issue.

http://www.ncbi.nlm.nih.gov/pubmed/18297716?ordinalpos=118&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Good luck and remember IF you are healthy, and it sounds like you are, your sides will be minimal.

bandman

[bandman54]

ps - I would stay away from fish oil as well.... it lowers your platelets and they will be way low anyway while undergoing tx.

You do want your blood to clot, right? lol.

bandman

[Marcia2202]

Thanks, thanks, thanks... I said the only 'animal protein' I'm getting is cheese. I'm getting plenty of protein from beans, lentils etc... Also some tofu.. I forgot to mention the organic whey protein... I will only start it once UND, as it has the particular brand I'm using a high level of lactoferrin.

There is only 30 IU vit E in my multivit, and I'm not adding any.... Having a low coagulation factor, I gave my extra vitamin E to my girls.... I have started on a daily vitamin K for that, too. I know E and K where both in the study you posted. But being a woman, having a low coagulation factor is really a monthly big drag. Scary...

Anyway, supplementing a deficiency is not the same as taking extra, when you have enough.

All the supplements I have now lined up and started taking are moderate amounts, so I'm sure they will not interfere with treatment. I'm not taking my fish oil, as it has a high vitamin A content. My krill oil doesn't.

Also I'm having my RF and uric acid etc checked, as I am suffering from stif hands and some joint pain... Waiting for the results.

Anyway, I'll be discussing all that with my doc in a few hours. YAY!!!

Marcia

[Marcia2202]

Yes to krill.... no to whale blubber.... ewwww and poor whales.  Don't feel sorry for the krill though... The only thing is that krill oil doesn't have vit D, that's why I usually take it in the summer and fish oil in the winter, when there is no sun.

Marcia

[zellyf]

Marcia,

Best wishes on your journey!

[Marcia2202]

thanks so much...

[bandman54]

you will do fine.

just stay healthy.

bandman

[Marcia2202]

Thanks, just got back from my doc and she okayed my supplements. She wasn't concerned about any of them, as I am not taking high doses of anything really. She is keeping and eye on my hemo, iron, transferrin, coag factor etc. I am actually taking 25mg of iron and 150mcg of vitamin K and she is monitoring that very closely. If my counts go up and my coag factor gets back to normal, she will have me stop the two. Next blood check in 2 weeks. Also all my baseline will be taken that day, including a new PCR. I'm also starting tx on that day. August 19th, our wedding day!

Marcia

[bandman54]

sounds good.

My doc is the same about the supplements BUT , I don't think that is a good thing...
I think it indicates that the treater is not knowledgeable about supplements.

That is not necessarily bad either as few of them know anything about supplements.

I noticed that you have a blood clotting, .. many, many supplements thin blood.
Go back and check each supplement, if any indicate thinning of blood  get rid of them.  Your blood will be thin enuf on tx.

just a note... I don't know if you are doing pegintron or pegasys,  but it seems to me that it takes longer for sides to show up on the pegasys than the pegintron, due to the different size molecule.  It takes 6 weeks for the pegasys to get out of your system after ceasing, therefore it seemed to me to take about 6 weeks to get totally in my system.  

best wishes!
bandman

[Marcia2202]

That's exactly what I have done... and I'm taking the vit K to help clot the blood... My doctor is monitoring this...

I'll be doing Pegasys 180mcg and Riba 800

Marcia

[bandman54]

sounds good.

you will lose less weight on the pegasys and you look very light.. so.. good choice.

I haven't lost a pound.... but am only on week 5.

yah, I thought that is what the vit K was for.

bandman

[Trinity4]

Are you still considering uping your Riba dose?  When you mentioned that it concerned me because of your blood work and your size, but I weigh around 115 and I'm taking 1000mg daily.  I noticed you were prescribed 800?  I don't know what the lb/mg dosages equate to but I'm thinking we are about the same weight?  Is 800mg sufficient?
Trin

[Marcia2202]

Just got back from my appointment, my doc will be treating me with 180 Pegasys and 800 Copegus for my weight and being geno 3. It corresponds to ca 14mg/kilo. I weigh between 56 and 58, it's going up and down all the time. 56 kg is around 124lb, I think.  

I believe 800 should be suffiecient. Here is something it says on the insert of Copegus. I believe that is what they go after.

HCV Genotypes  
HCV 1 and 4 - Irrespective of baseline viral titer, treatment for 48 weeks with PEGASYS and 1000 mg or 1200 mg of COPEGUS resulted in higher SVR (defined as undetectable HCV RNA at the end of the 24-week treatment-free follow-up period) compared to shorter treatment (24 weeks) and/or 800 mg COPEGUS.

HCV 2 and 3 - Irrespective of baseline viral titer, treatment for 24 weeks with PEGASYS and 800 mg of COPEGUS resulted in a similar SVR compared to longer treatment (48 weeks) and/or 1000 mg or 1200 mg of COPEGUS (see Table 2).  

[bandman54]

your just a geno 3?!

lightweight!

bandman

[orleans]

how 'bout a few "to dos" , thanks, jerry

[bandman54]

do drink lots of water.
do drink protein.
do take tylenol.
do excercise.

bandman