PS with added Alinia off-label, stage 4 cirrhosis
husband's stats:
geno 1, baseline VL 17.2 million
4wk VL 9,310
8wk VL 71
12wk VL detectable <50
13wk VL UND <5
1b
starting VL 245,000
4 week <15 Taqman Test
12 week UND Taqman Test
Grade 0 Stage 0
stopped treatment at 27 weeks 8 April 2009
Next PCR 8 October 2009
No riba reduction during treatment
AST and ALT normal from Week 12
genome 2b
base 538,000
4 week UND
@ week 8 now 12 week VL in 4 weeks. will post
Genotype 1a
Baseline: 120,000 IU/ml (bDNA test)
Week 4: 2900 IU/ml (Taqman test)
Week 12: detectable but not quantifiable <15 IU/ml (Taqman test)
Week 15: UND
Did 72 weeks
SVR
I've also read about stopping treatment after 24 weeks if you reach UND at 4 weeks. I believe they have even changed the protecol in parts of Europe as a result.
I was at a viral load of 24 at 4 weeks so I am sticking out the 48 weeks, as tempting as 24 weeks shorter treatment sounds.
k
I have read about some studies now that show low starting VL and UND at 4 wks have been able to reduce TX to 24 weeks.
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I thought being able to quit at week 24 was for those on PI's. If your UND at week 4 with SOC you can stop at 24? I never heard of this before.
starting VL 345.000 4 week und <60 per sensitivity of test. 12 week UND <5.
I am now at 40/48 1a grade 1/1.
I did not get tested before 4 weeks and I think that is fairly standard.
It would have been nice every 2 but UND at 4 wks upgrades your SVR odds to 90%
I have read about some studies now that show low starting VL and UND at 4 wks have been able to reduce TX to 24 weeks.
It is tempting for me because of all these crummy side effects but I would never forgive myself if I stopped early and was not SVR. I did drop my Riba does at 24 weeks due to anemia problems even with rescue drugs.
Still waiting......I won't get retested until 12 weeks. Now at week 8. March 23rd is the red letter date.
Of those who where not UND at week 4 when did you become UND?
Gentype 1A
My VL jumped from 8 million to 75 million b4 tx.
4 week PCR= 330
7 Week- UND.
Stage 2 Grade 2- mild activity
baseline 9,450,000
4 weeks 24
geno 1B
Genotype 1b
Baseline VL: 30,100
4 wk VL: UND
Opps and another important thing... what is your Genotype?
Baseline 848,000
4 week 38,600
Baseline was 6,000,000
4 week was UND
Base line 1,300,000
4 weeks 80