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Avatar universal

SVR or Relapse?

As more and more members are either reaching SVR or relapsing, I thought we could start a thread which allows those who have completed treatment to post their personal results. This may be helpful to others who will be starting treatment soon.

If you choose to participate, please follow this outline:

Gender:  
Ht/Wt:
Genotype:
VL at start:
What Treatment:
How Long:
SVR or Relapse:  
Comments:  (if any)



Feel free to suggest additional info.
Nan
Best Answer
Avatar universal
Gender: Male
Age: 59
Ht/Wt: 6' 220#
Genotype: 2b
VL at start: 125,000
What Treatment: Sovaldi/Ribavirin
How Long: 12 weeks
Date completed 04/22/14
SVR or Relapse: SVR
Liver Status:  F2-3 on biopsy 06/13 Fibroscan 10.2 kPa 07/14
Naive or Prior treatment:  Naive

Additional Comments:  
No side effects to speak of. I was able to XC ski regularly and cycle 200 mi+ a week while on treatment. Hemoglobin went as low as 13.9 but no anemia
257 Responses
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475555 tn?1469304339
Yup, UND at EOT+15 mos. Plus all liver functions intact by recent blood analysis. So things are steady-state and I'm finally able to relax about it. I don't like to count my chickens, though, so I will have VLs done every year, and of course continue the bi-annual color US to check for HCC, portal hypertension, etc. The reports on UND people's fibrosis continuing to advance (not many, but some) will keep me on watch the rest of my life.

Cheers, Sandi, and thanks for asking.

Mike
Helpful - 3
3 Comments
Congratulations Mike! You did it! I am so happy for you! You are now an official Dragonslayer!
Do I get a button?
You come to San Diego, you get a button!
317787 tn?1473358451
Thinking of you all, couldn't have gotten to SVR without all of you, much love, Dee
Helpful - 2
475555 tn?1469304339
:-)
Helpful - 2
Avatar universal
Gender: Female
Age: 55
Ht/Wt: 5'11"/225
Genotype: 1A
VL at start: 775000
What Treatment: Harvoni/Ribavirin
How Long: 24 weeks
Date completed 8/25/15
SVR or Relapse: SVR 24 (finally!!!!!)
Liver Status:  Early cirrhosis
Naive or Prior treatment:  
3 previous treatments:  interferon 3 x week/Ribavirin 6 months 1999, boceprevir/interferon/Ribavirin 24 weeks 2012, Sovaldi/Interferon/Ribavirin 12 weeks 2014.
Additional Comments:   I am incredibly grateful and still can't believe the virus is dead!  The first two treatments were really rough. I'm so glad the cure for most is so much easier and has such better cure rates!

Positives: Having gone through Hep C and all that goes with it has taught me so much about courage, bravery, perseverance, faith, patience and trust.  I have met some incredible people.  Thanks to everyone on here who chased the dragon with me and for my spouse and all spouses who helped all of us with the fight.  I also offer up prayers and a moment of silence to all those who fought the fight and weren't able to receive this incredible gift that I have received. To those in the fight and those yet to fight, stay strong and slay that dragon!
Helpful - 2
Avatar universal
Last week I got my EOT + 15 month results and I'm still undetected. NOW I can breathe easy. The 24 week test for some reason felt like it was a dream and I really didn't consider myself out of the woods. Now that I have 2 undetected tests I'm starting to believe it. Liver functions are on point and all my labs are excellent though I will have to have yearly scans since I was Stage 3 at the start of this last treatment.
Helpful - 1
1 Comments
Congratulations on being cured!
Avatar universal
Gender: M

Age: 60 at start of treatment in January, 61 now

Ht/Wt: 5'8" 195

Genotype:

3a also Stage 4 (cirrhosis)

VL at start:

5,000,000 +

What Treatment:

MK3682b (Grazoprevir, MK8408, MK3682) + ribivirin

How Long:

16 weeks

SVR or Relapse:  

SVR 24, received the news today!
Helpful - 1
1 Comments
Congratulations!
Avatar universal
In early January, I began a clinical trial for genotype 3, 16 weeks of MK-3682B plus ribivirin.

The drug MK-3682B consists of three drugs: MK-5172 (aka grazoprevir), MK-3682, and a newer drug MK-8408 (some are being given MK-8742 aka elbasvir).

Received good news this morning: SVR 12

Helpful - 1
7469840 tn?1409845836
Oh what wonderful news Nan! Wow you two have been through the wringer, but your persistance has finally paid off! What a great birthday and Valentine's Day gift!
Helpful - 1
Avatar universal
When I started this thread 18 months ago, I was hoping to one day add my husband to the list as reaching SVR12.
Well, that day is finally here!!!!   Today is his 70th birthday and he just got his 12 Week post Harvoni treatment lab result - UNDETECTED!  
Gender:  Male
Ht/Wt:  5'10'' / 185 lbs
Genotype:   1B  (previously told he was 1A)
VL at start:  96,000
What Treatment: Harvoni  
How Long:   24 weeks
SVR or Relapse:  SVR12!
Comments:  (if any)
My husband is a liver transplant patient. He received his new liver in June, 2012.  Unfortunately due to recurrent Hep C, within 7 months, a biopsy showed he had cirrhosis of the new liver again. A six month treatment with Sovaldi and Ribavirin (low dose only) unfortunately failed. Three months later he had a bad fall and fractured his femus and humerus which delayed treatment with Harvoni for another six months. He finally started treatment in June, 2015 and completed treatment in November, 2015.  It was a very difficult year but he hung in there and now on his 70th birthday he got the news - it was all worth it  -  SVR12!
Hallelujah!  Praise God!
Helpful - 1
1 Comments
Praise God, indeed!  You and you husband have been an inspiration to so many of us.  So glad to hear your wonderful news.  nOw BOTH of you step up onto the Dias and receive his Dragon Slayer Supreme Insignia.  Boy, have you both earned it!!!!

Love and Blessings,  Pat
683231 tn?1467323017
Bump
Helpful - 0
Avatar universal
male
6.0   170lbs
1b
4 million
48 weeks solvaldi and Riba
SVR
Helpful - 0
475555 tn?1469304339
Is this thread still active? If so, I would suggest that the result of an EOT+12mos. VL be added to people's data, especially since there are new meds which produce short-term SVR but then a relapse occurs.
Helpful - 0
1 Comments
Yes, still active, did you get your result back yet?
Avatar universal
Hi all. I am male, 200 lbs, Genotype 2, 18,000 particles(highest ever measured was 58,000) at start of 3 month Ribavirin/Sovaldi. Fibroscan 10.7 kpa. I have just received the 6 month eot results. Free at last. No virus detected since 2 weeks into start of treatment last September.
  ALL bloods right smack in the middle of normal. Finally, I'm a "normy". Ribavirin sucked. Big side effects, mainly anemia.
    So glad I am done. I am beginning to feel more energy that I have had in years! I'm 63 years young. YAY! Leagh88
Helpful - 0
Avatar universal
You know life is not always fair.  
I'm so saddened to hear this and almost in disbelief
You've both done everything right and to no avail.
I'm so very sorry.
Know you are both in my thoughts and prayers❤️
K
Helpful - 0
683231 tn?1467323017
Hoping the best for both of you and that this time will be the one

Lyn
Helpful - 0
6708370 tn?1471490210
Stay strong and this time will be the one! I am so sorry that it didn't "take" last time but the 2 of you are troopers and the treatments just get better and better

Sending all my best wishes for an easy treatment and for you to finally be able to say SVR! at long last

~ Linda
Helpful - 0
317787 tn?1473358451
I agree with Idyllic, I remember how damn hard it was for you and am so grateful you are SVR!
Love
Dee
Helpful - 0
2 Comments
Hi All
It's been a while since I last posted that my husband had finally reached SVR12 after his 6 months of Harvoni. We were so excited to know he was finally cured of this terrible Hep C virus.
But it was not meant to be. Two months later (week 20 post treatment), I noticed he was having old familiar symptoms (HE) so I asked his doctor to retest him and my worst fears were realized - his Hep C was back. I don't think I need to tell you how disappointed we are.
We believe he will be starting a new treatment sometime  in July (Sovaldi and Daclatasvir). This will be his fourth attempt to rid himself of this virus.
We ask for your good thoughts and hope that this time he will finally beat this monster.  
Hi All
It's been a while since I last posted that my husband had finally reached SVR12 after his 6 months of Harvoni. We were so excited to know he was finally cured of this terrible Hep C virus.
But it was not meant to be. Two months later (week 20 post treatment), I noticed he was having old familiar symptoms (HE) so I asked his doctor to retest him and my worst fears were realized - his Hep C was back. I don't think I need to tell you how disappointed we are.
We believe he will be starting a new treatment sometime  in July (Sovaldi and Daclatasvir). This will be his fourth attempt to rid himself of this virus.
We ask for your good thoughts and hope that this time he will finally beat this monster.  
6708370 tn?1471490210
Can't remember if I did this or not so here's the data Nan

Gender:   F
Ht/Wt: 5' 9"  138
Genotype: 1B
VL at start: 4 million
What Treatment/How Long:: 12 weeks Sovaldi relapsed; A year later, 12 weeks of Harvoni & Rebavirin
SVR or Relapse:  SVR
Comments: Could never have navigated or been cured without the kindness of my fellow Heppers

~ Linda
Helpful - 0
Avatar universal
Thanks Idyllic!  Good to see ya hope you are well.

J
Helpful - 0
766573 tn?1365166466


So glad you obtained SVR. (!!!)
I remember when you were on triple and had to deal with iron and phlebotomies. It was awful and you kept chugging along.
Helpful - 0
Avatar universal
I am still not over the novelty of my SVR. It takes awhile for those of us who have had it for decades, and have been through several treatments. You have been through the ringer. Just want to say congrats again, and enjoy!!
Helpful - 0
1 Comments
thanks 48 very hard for me to still believe!!!!
Avatar universal
Gender:  Female
Age: 53
HT/WT: 5'7" 150 lbs
Genotype: 1b, CT
VL at start: 1,261,720
Treatment: 24 weeks Harvoni
Date completed: Dec 13, 2015
SVR or Relapse:  SVR12 (I can't believe I just typed that)!!!! yay me
Liver Status:  Compensated Cirrhotic Meld 5
All blood work normal with the exception of Iron levels which made me think I was going to relapse.

Prior to Prior treament- diagnosed with hemachromatosis and pct.  So I had to have weekly phlebotomies in order to reduce iron and ferritin levels before starting tx.  I can't remember but I think I did that for about 3 months before I could start the dreaded triple therapy treatment.

Game plan was for 48 weeks of Victrellis, Riba, and Interferon.  After about 12 weeks my blood work started to go out of wack.  Had to start taking weekly Neupogen shots, boy that was fun, because my WBC were tanking.  Then at week 36 my hepatologist stopped tx due to my rising ALT/AST and they were about 150 each.  So @ EOT VL not detected, 3 month EOT not detected, and final 6 month EOT was DETECTED!  I couldn't believe it.  VL was around 4000 so I thought it was an error so we reran it and it was approximately 800,000.  

So now just have to deal with the iron levels through phlebotomies.  I can take that any time of the day.  So happy this disgusting disease is out of my body and I can start living my life again.  

Thanks to all of you who have supported me all these years.  You know who you are and luv ya guys!!!!!!!!!
Helpful - 0
Avatar universal
Gender : Male
Age :44
Genotype : 1A
Vl at start : 4.2 Mil.
Liver status : biopsy : 0-1 , Fibroscan 5.2 .
Naive or Prior tx : Treatment Experienced ( Riba & inf )
what tx : harvoni 12 weeks ( generic from bangladesh called " lesovir - c " )
Svr or relapse : Svr 11 weeks .
All blood work normal .

travelling so got my 12 weeks post tx done a week earlier , ie the svr 11 status

Best wishes to all  . . .

God bless and warm regards .

Helpful - 0
1 Comments
Great excellent, you have done it
Avatar universal
Gender: Male
Age: 36
Genotype: 1b
VL at start: 2 mil
Liver Status:  f2 biopsy
Naive or Prior treatment:   Naive
What Treatment: Viekira pak
How Long: 12 weeks
SVR or Relapse: SVR – EOT 24 weeks – UNDETECTED, all blood labs normal.
Helpful - 0
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