Searching for Indiana entry on protease nm283 and vx950

[shads]

Today was my first visit to the site . I saw an entry from someone who was being treated by /involved in a clinical trial with Dr. Paul Kwo at the Indiana University Medical Center. I have searched the site again and could not locate the conversation and hence the information. I too have meet with Dr. Kwo and learned about the trial using peg-intron and rebetrol, the IDEAL study and a future protease study.. I am curious about the vx x 950 and/or nm283--I use there terms tenatively as today is the first time I have seen them. I assume they are forms of protease. I would like to hear the perspective/experience  of a HCV patient. I have a low vira-load( btwn 250,000- 800,00 and no scarring yet.

I have been to various sites and feel even more intrigued by these alternatives. If the previous Indiana writer is out there, i would love to hear from you; otherwise, any comments would be appreciated. I have read the stuff from the EASL conference.

One last question: Has anyone tried transfer-factor?

[johnisme]

Hello and welcome, im also a patient of Doctor Kwo at IU. If you go down the list of questions to the article titled "End game for protease inhibitors" dated 9-26-2005 and go through the list you will find alot of info on that subject. Good luck to you....John

[shads]

thank you.

[miked]

Hi Shads.  I'm the guy you were asking about.

Do go back and read the thread, "End Game for Protease Inhibitors".  The was a lot of good information exchanged.

Dr.Kwo @ IU Med. Center is involved in many clinical trials.  To my knowledge he has not participated yet in a PI clinical trial.  I asked about VX-950 and NM283 and was told to wait for the Schering PI.....why?  From what I can read Schering is just coming out of the gate and is 2 years behind Vertex and Idenix.  Paul Kwo is a really good doc....does he know something we don't know or is Schering forcing its way into the PI market?

I just hope that one of these works, soon.

miked.