Space, do you think you can buy the Narigenin extract in a health food store?

[St. George]

I am going to start drinking grapefruit juice but I wonder if vitamin shop carries the flavanoid Naringenin.

[Biomath]

Apigenin look for this take 500 mg per day or more

[kickboxingmom]

I am so sorry about posting twice.

[kickboxingmom]

Tuesday, 10 June 2008 Search    

            
Magazine - The Hep Factor

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Home  News  Treatment News  Grapefruit May Curb Hepatitis C Grapefruit May Curb Hepatitis C        
Sunday, 04 May 2008 22:24  
May 1, 2008 — Grapefruits may inspire a new treatment for hepatitis C, a leading cause of liver disease.

Preliminary lab tests show that naringenin, a compound found in grapefruit and other citrus fruits, may curb the spread of the hepatitis C virus by 80%.That might give healthy cells a chance to regenerate and stem the tide of hepatitis C's spread.

So say researchers including Yaakov Nahmias, PhD, of Harvard Medical School. They note that there is a "pressing need" for new treatments for hepatitis C infection because current treatments don't always work and can have side effects.

Nahmias and colleagues knew that naringenin counters very low density lipoprotein cholesterol (vLDL, a form of "bad" cholesterol), and they suspected that the hepatitis C virus may "hitch a ride" on cholesterol.

That theory held up in test tube experiments. Naringenin curbed vLDL cholesterol, which made it harder for the hepatitis C virus to spread.

But you might not be able to eat enough grapefruit to get that benefit.

The gut doesn't absorb naringenin very well, so a naringenin drug, delivered intravenously, would be a more likely treatment, the researchers conclude. In further lab tests on mice, naringenin wasn't fatal and didn't raise liver enzyme levels, so an intravenous treatment might be a possibility, the researchers report in May's edition of Hepatology. But it will take more work to develop a naringenin drug for hepatitis C.

Grapefruit may affect certain types of medications, so a grapefruit-based approach might not be right for all patients.

SOURCES: Nahmias, Y. Hepatology, May 2008; vol 47: pp 1437-1445; News release, John Wiley & Sons Inc; WebMD Medical Reference from Healthwise: "Grapefruit Juice and Medication -- Overview."

http://www.medscape.com/viewarticle/573831?sssdmh=dm1.348594&src=nldne


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Magazine - The Hep Factor

Web Version | Print Version

Magazine - Hep C Review

Part 1 | Part 2

Hep C Community News

Magazine - Good Liver
Popular Articles & InformationHepatitis C Video
Liver Information - Strategies for Preventing Liver Damage
16 New Treatments For Hepatitis C.
Welcome to AHCS - Australian Hepatitis C Support
Hepatitis C linked to severe kidney disease
Home  News  Treatment News  Grapefruit May Curb Hepatitis C Grapefruit May Curb Hepatitis C        
Sunday, 04 May 2008 22:24  
May 1, 2008 — Grapefruits may inspire a new treatment for hepatitis C, a leading cause of liver disease.

Preliminary lab tests show that naringenin, a compound found in grapefruit and other citrus fruits, may curb the spread of the hepatitis C virus by 80%.That might give healthy cells a chance to regenerate and stem the tide of hepatitis C's spread.

So say researchers including Yaakov Nahmias, PhD, of Harvard Medical School. They note that there is a "pressing need" for new treatments for hepatitis C infection because current treatments don't always work and can have side effects.

Nahmias and colleagues knew that naringenin counters very low density lipoprotein cholesterol (vLDL, a form of "bad" cholesterol), and they suspected that the hepatitis C virus may "hitch a ride" on cholesterol.

That theory held up in test tube experiments. Naringenin curbed vLDL cholesterol, which made it harder for the hepatitis C virus to spread.

But you might not be able to eat enough grapefruit to get that benefit.

The gut doesn't absorb naringenin very well, so a naringenin drug, delivered intravenously, would be a more likely treatment, the researchers conclude. In further lab tests on mice, naringenin wasn't fatal and didn't raise liver enzyme levels, so an intravenous treatment might be a possibility, the researchers report in May's edition of Hepatology. But it will take more work to develop a naringenin drug for hepatitis C.

Grapefruit may affect certain types of medications, so a grapefruit-based approach might not be right for all patients.

SOURCES: Nahmias, Y. Hepatology, May 2008; vol 47: pp 1437-1445; News release, John Wiley & Sons Inc; WebMD Medical Reference from Healthwise: "Grapefruit Juice and Medication -- Overview."

http://www.medscape.com/viewarticle/573831?sssdmh=dm1.348594&src=nldne





  


  Site, Article & Information DisclaimerAll information and articles provided on our website and forums are to be used as a guideline only. For your own safety, please always consult with a doctor or specialist before making any decisions regarding your health care. By visiting this website you instantly adhere to this policy.Copyright © 2008 AHCS - Australian Hepatitis C Support
  wn safety, please always consult with a doctor or specialist before making any decisions regarding your health care. By visiting this website you instantly adhere to this policy.Copyright © 2008 AHCS - Australian Hepatitis C Support
  

[geok]

NARIGENIN IS AVAILABLE AT

LLOYD WRIGHT.COM

SO IS THE CURE FOR HEP C

[evangelin]

Please let us know if you get a word on the subject from HR.  I had thought about seeing if you could talk to him but hated to ask.  I would greatly appreciate knowing anything you find out.
Have a lovely day,
Ev
P.S. I have alway loved your handle. "Forseegood" is such an uplifting name.

[Forseegood]

this sure *sounds* impressive...unfortunately, other things have to, but maybe there is something to this stuff...you know who I'll run it by, sure like to know what HR thinks...

[Alek07]

Check out this link: www.medicalnewstoday.com/articles/96261.php

[gauf]

Can someone tell me more about Naringenin? First i have heard of it.

[spcecst2]

thanks for the info!!!!!!!!!!!!!!

[evangelin]

It took me a while to find it but Swanson Health products carries 100% natural Naringenin from grapefruit.  I know this could be possibly quite dangerous with certain meds so be careful if anyone tries it.  I will let you know if it does anything good for us.  My husband doesn't have years to wait around for an FDA approval because his liver is too far along in cirrhosis. We will try this.

[evangelin]

Now I'm thinking grapefruit seed extract is the way to go.  I think the citrus bioflavonoids stay away from the grapefruit because of drug interactions. The grapefruit seed extract seems to contain naringenin.  I'm just looking for backup in addition to the grapefuit and juice. Still hoping some others will weigh in on this.  It seems so hopeful.  We need every edge we can get.

[evangelin]

First of all, I spelled bioflavonoids wrong.  Here is the info label on the twin labs and so far it looks more promising than anything else I've found.

Supplement Facts
Serving Size: 2.00 Caps
Servings per container: 50.00  

  Amount Per Serving  % Daily Value  

Citrus Bioflavonoid Complex (containing 50% total bioflavonoids consisting of flavanones [hesperidin, eriocitrin, naringen and naringenin], flavanols and flavones)) 1,400.00 mg *

Rutin 100.00 mg *

1,400 mg. is the most I've seen and it includes the word naringenin.  It is easy enough to consume some grapefruit and grapefruit juice except for the possible drug interactions.  I talked to a pharmacist about the Nadolol my husband takes for a non-bleeding varicies and he said that grapefruit wouldn't affect this drug but would affectpropranolol which some people take for varicies.  This particular pharmacist said that it is only a handful of meds that are a problem with grapefruit.  

[evangelin]

I'm hoping some of the real smarties around here will help us figure out how to get this naringenin thing figured out.  Twin labs has citrus bioflavanoids and it says it's the strongest available but I don't know about this.  My ears are perked and I'm digging for info.  I sure wish HR. was here.  
St. George, hope you are doing well with treatment. Let us know how it went with the Alinia when you can.