Aa
Aa
A
A
A
Close
Avatar universal

Starting clinical trial

I will be taking either:

sofosbuvir and gs 5885 for 12 weeks or

sofosbuvir and gs 5885 and ribavirin for 12 weks  or

sofosbuvir and gs 5885 for 8 weeks

I have no prior tx, am genotype 1a, have had hepc for over 35 years

any ideas of which above would be best...? what is the expectation for SVR

thanks in advance
Best Answer
1815939 tn?1377991799
Here is a link to a report about the drugs you will be taking. The SVR rates are included. Just copy and past it into your browser:

http://seekingalpha.com/news-article/6421611-gilead-reports-interim-data-from-phase-2-lonestar-study
9 Responses
Sort by: Helpful Oldest Newest
Avatar universal
Best of luck with tx.  You have an excellent chance here.  Keep us posted and let us know how you are doing.
Helpful - 0
1815939 tn?1377991799
Keep us posted on how things go with your trial. Here's hoping your treatment will be smooth and successful.
Helpful - 0
Avatar universal
I'll find out when i get first dose end of may...

I would like the 12 weeks without riba.....but its a roll of the dice... best of luck to us
Helpful - 0
Avatar universal
sorry, I meant sofosbuvir and 5885 of course
Helpful - 0
Avatar universal
I have also just started this study - but here in the UK it's 12 or 24 wks w or without Riba. I got the GS5885 for 12 wks with Riba. Happy to compare notes. where are you based and which arm did you get? I too am 1a treatment naive; Hep C 30+ yrs. having a few nausea probs but figuring out what to eat for the best.
good luck
Raina M
Helpful - 0
Avatar universal
Thanks for encouragement. I have psoriasis and depression hx so interferon tx was never an option for me. I had this for over 37 years.... so im very thankful for this chance.
john
Helpful - 0
Avatar universal
Your chances are excellent being treatment naive. I  finished up the gilead 12 week study with GS5885 (ledipasvir)/sofosbuvir/riba 8 weeks ago. I finally went UND on this Study trial. This is my 4th attempt with the first 3 Tx attempts (with interferon) being failures. Please take advantage of this opportunity.
Helpful - 0
1815939 tn?1377991799
Welcome to the forum.

Here is a thread all about the drugs you will be taking. If you read through the entire thread maybe you will get some of the answers to your questions. I will also look for some other information and post it if I can find it. In the meantime, here is the thread. Just click on it and I think you will find a lot of information:

http://www.medhelp.org/posts/Hepatitis-C/Starting-Sofosbuvir-GS-5885/show/1875802
Helpful - 0
Have an Answer?

You are reading content posted in the Hepatitis C Community

Top Hepatitis Answerers
317787 tn?1473358451
DC
683231 tn?1467323017
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.