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Thalidomide w/ Combo Yields complete remission for nonrespondors
by latecomer, Jan 12, 2007 12:00AM
Anyone else know more about this?
"A Brazilian case study report indicates that by adding thalidomide to standard combination therapy, six HCV-positive, prior non-responders experienced total remission of their chronic Hepatitis C. Known to cause severe congenital abnormalities, thalidomide's safety and efficacy must be investigated in future Hepatitis C trials before being considered as a viable treatment."
http://hepatitis-central.com/mt/archives/2006/12/reports_of_new.html
Though this sounded interesting. Thalidomide appears to have anti-inflamatory properties and increase T cell production.
Side effects:
http://www.bccancer.bc.ca/NR/rdonlyres/FB65F421-BF1F-4763-A4EF-593F5054D234/19510/Thalidomidemonograph_3Nov06.pdf
"A Brazilian case study report indicates that by adding thalidomide to standard combination therapy, six HCV-positive, prior non-responders experienced total remission of their chronic Hepatitis C. Known to cause severe congenital abnormalities, thalidomide's safety and efficacy must be investigated in future Hepatitis C trials before being considered as a viable treatment."
http://hepatitis-central.com/mt/archives/2006/12/reports_of_new.html
Though this sounded interesting. Thalidomide appears to have anti-inflamatory properties and increase T cell production.
Side effects:
http://www.bccancer.bc.ca/NR/rdonlyres/FB65F421-BF1F-4763-A4EF-593F5054D234/19510/Thalidomidemonograph_3Nov06.pdf
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I think that there will be an investigational follow up by some one,but as so far it's just six patients in Brazil with no further verification,I would,until a bigger study comes along file under 'amantidine'!