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Read more here:
http://www.hcvadvocate.org/hepatitis/hepC/hcvinformation_2006.html
the vitamin C you should not take with meals or snacks containing any iron as they will cause the iron to become bioavailable.
many fiber foods such as fruits and vegetables have iron but it is non-heme type...not easily absorbable.However if you eat heme iron (meat/eggs) with it, or anything acidic or containing vitamin C..then you make the bound iron become available...
so this is the chief supplement you need to rethink.
Not saying don't get some C...because it is helpful to cell health and as an antioxidant...but better you should eat a citrus snack alone or with other non-iron foods.
trouble is, everything has some iron in it.
Eating an orange alone is your safeest bet. Why do you think you need a gram and a half a day of C?
I am like a dog with a bone right now trying to get info as I try to wrangle a spot for the Advance trial. That is why I want to know about rescue drugs...because if they don't allow them and you are going in low, it seems pretty likely they will fall during treatment.
I will either give it up or stay in "tenacious D" mode once I get a bit more info. Vertex isn't talking and the other couple of centers that I have talked to didn't know for sure yet.
Thanks.
Reducing Iron Stores
Elevated serum iron levels are often found in people with hepatitis C and cause further oxidative damage to the liver. Certain nutritional supplements have shown evidence of reducing serum iron levels. To help keep serum iron levels in the low normal range of 30 to 80 ng/dL, high doses of green tea polyphenols and high-allicin garlic may be beneficial.
Lactoferrin, a subfraction of whey protein, may be especially beneficial as an adjunctive treatment for serum iron overload in hepatitis patients. Lactoferrin is a potent antioxidant, antiviral agent, and scavenger of free iron. In addition, lactoferrin is directly involved in the upregulation of natural killer cell activity, making it a natural modulator of immune function (Yi M et al 1997; Ikeda M et al 1998, 2000). As an immune booster, lactoferrin has been shown to work synergistically with interferon to reduce the viral load (Ishii K et al 2003).
Taking 300 mg of elemental calcium can reduce iron absorption by as much as 50 percent. When eating iron-rich foods, hepatitis C patients should consider taking a high-potency calcium supplement at the same time (Hallberg L et al 1991).