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Treatment Update for folks with High Viral Load

Started treatment 10/01/11
geno type 1a
liver biopsy 2/3
incivek
2004 relapser
2004  pretx 438000
2004  tx 0

2008  4,031,300
2009  11,495,000
2010   34,238,000  

10/08/11   470 one week
10/28/11  <43 DET four week  
11/28/11  <43 UND eight week
12/23/11  <43 UND twelve week
02/23/12  <43 UND twenty four week

11 Responses
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2062453 tn?1350332942
Hi John: Yes, I'm still treating. Today I started week 22 (of 24). My treatment ends on 4/9. I'll get VL tests at 2 weeks, 4 weeks, and 6 months post treatment. If my virus went into hiding (like it did in 2009) I'll know within a few weeks after stopping treatment, which is why I'm getting a 2-week post treatment VL test. If I forget to message you with an update, please message me or check frijole's chart. Best Wishes, GB
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Avatar universal
Wow - thats an encouraging number - are you still treating
please let me know how it goes

Sorry I do not have any information to back up the 80% number its just what my nurse said

Blessings
John
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2062453 tn?1350332942
Hi Will: Point taken. Here is a source document supporting the assertion of a 99% cure rate if UND 6-months after treatment.

http://hepatitisdoctor.com/

Specifically, in the first paragraph, which discusses telaprevir, the document states, "If your HCV-RNA is undetectable 6 months after your last injection of interferon, you have a 99% chance of permanent cure." Cheers, GB
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Avatar universal
"passing"
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Avatar universal
Your nurse told you.?
If you are going to relay facts and figures to the group ,it is always advisable to  copy the data you are getting  the information from,so as not to be just paaing on what someones opinion may be
best...
Will

http://www.colloquium.eu/congres/11PHC/presentation/Monday_Amphi_bleu/A_ALBERTI.pdf     (4th slide)
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2062453 tn?1350332942
A couple of weeks ago, my nurse told me the latest data is indicating a 99% cure rate for people who are UND 6-months post treatment. I don't know how large their sample size is, but her comment was very encouraging.
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Avatar universal
Thanks for the information Will - The nurse told me I had about an 80 percent for SVR with these numbers - I really appreciate all of the  infromative posts you have provided on this site,  
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Avatar universal
Just to add to my last post...in those same trials RVR  was still  the most important success predictor  irregardless of baseline VL.

Will
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Avatar universal
Yes,it would seem that amount of baseline VL is not near as much of a concern treating with one of the "protease inhibitors" as it once was tx. with only PEG/RIBA,however there is trial data that shows that with a higher viral load the SVR rates were somewhat higher with the extended treatment time( 48 vs.24wks.) ,but only slightly.

Good luck the rest of the way and congrats on the UND.

Will
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Avatar universal
I am on shot 26 tonight
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2062453 tn?1350332942
Barmuckity: Congrats on UND at week 24 and thanks for the update!

You started with the highest viral load of anyone on frijole's spreadsheet. I started two spots behind you at 22M. Your success is motivational.

Was your treatment over at 24 weeks or are you on the 48 week treatment? Cheers, GB
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