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What %are cured with interferon and ribavirin

There seems to be alot of people on this site that are non responders or have taken 3-4-5 treatments and still have HCV. What % get the Interferon/ribavin and are cured?. Cure meaning they no longer have HCV for the rest of their life, unless reinfected?
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Avatar universal
I tend to agree with with Peg on Peg !!!  I personally am the least interest in a Liver Transplant however receiving news the other week that I am now and the beginning of end stage liver disease, there is probably not much I wouldn't do.  So, I've begun a Clinical Trial that is designed for NR's from the last TX.  I went into that one knowing that as a 1B, the odds were terribly high for me but figured my positive attitude would overcome that.  Sadly, I didn't even get a reprieve.  In the meantime, my liver has deteriorated to a stunning level and my viral count has risen to unimaginable.  Therefore, I feel very very blessed to be a participate in this Clinical Trial with the Tealapvirl
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408795 tn?1324935675
If you want studies, you can go to pubmed and do some research.  good luck  
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Avatar universal
These numbers are compiled on a global scale..these are the cure rates reflected from reports from around the world.  We are at the mercy of those reporting..these are the numbers that we reference because we've never heard anything different.

"I just dont want to jump into some thing before knowing the odds."  That statement puzzles me.  If you're infected, if the function of your liver is compromised, if you are still alive enough to care about being alive, then you treat.  It will not go away by itself.  It will continue to feast on what's left of your liver until there is nothing left to eat.  At this point, do "odds" matter?  It is, or it isn't. It works or it doesn't.

You see ppl here who treat time & time again, trying to clear.  There is one guy here who has treated 10 times, trying to kill the virus that's killing him.  Why do you think these people continue to come back for more?  With the horror stories of side effects that you read here, why do these people contnue to do this to their bodies?

Statistics are averages.  I, myself, am way ahead of the curve as a G-1a.  I cleared the virus somewhere between week 4 & week 8.  Starting with a viral load count of 13,500,000, this is a staggering response.  My response will someday be part of the statistics that are quoted here.

I wish you luck..& I hope the odds are with you.
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Avatar universal
No, the stats quoted are per studies and maybe someone will supply some links, or you can do your own web research.

For starters, the number one pre-treatment predictor of success is your genotype. Other factors include sex, age, amount of liver damage (biopsy stage), nationality/race, BMI, and whether or not you are insulin resistant -- the latter showing more and more importance per recent studies.

-- Jim
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Avatar universal
So are these Anecdotel figures?, or  is there some  real science behind these numbers?Where would I find studies that give real world numbers? Does anyone keep track of everyone using these drug therapies and outcomes? I just dont want to jump into some thing before knowing the odds.
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Avatar universal
From observation over a three year period, I would guess that our SVR rates here are probably better than the stated averages, probably because those here by their very presence tend to be more involved and therefore more compliant in taking the drugs, not to mention better informed than average. The stated averages are 40-50% SVR for geno 1's and 80% for geno 2's and 3's. Again, my guess is we beat those averages by a bit, but never did any math.

-- Jim
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Avatar universal
The answer depends upon which genotype of HCV the person is infected with. For people infected with genotypes 2-4, the cure rates are 80-90%. For people infected with genotype 1, which is the most common form in the US, the cure rates are approximately 50%. Since many of the posters on this board are in the U.S., you're seeing that lower cure rate reflected.

There are many additional factors, such as race, age, gender, bmi, degree of liver damage, that affect the chances of cure in a particular case. So you can't really get a sense of your own likelihood of cure without talking to a doctor who is knowledgeable about HCV treatment if that is the reason for your question.
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