Hi I hope this helps you, I found it in Lucinda's blog, I thought it was really helpful. I hope it will help you as well. Dee
http://www.medhelp.org/posts/Hepatitis-C/HCV-UND---SVR-NEW-INFO/show/2527772
Hang in there, praying for you, Dee
Hahaha. How many different ways can we say the same thing??
Oops! I put <12 and it should have been <15. Thanks for the correct information!
Pat
And there is the correct answer.
Thanks hrsepower!
Question 2. What do these test results mean: “<15 Detected” or “<15 Not Detected”?
A “<15 Detected” means the assay was able to detect HCV RNA but was not able to accurately quantitate the viral load. A “<15 Not Detected” means the assay did not detect HCV RNA (Target Not Detected).This test is performed using the COBAS® AmpliPrep/COBAS® Taqman® HCV Test v2.0. The lowest viral load this assay can accurately quantify is 15 IU/mL, but the limit of detection is 10-13 IU/mL. Therefore, we can qualitatively report detection even if the viral load is under 15 IU/mL.
http://education.questdiagnostics.com/faq/FAQ22v1
Don't wish to be disagreeable, but "undetected" means just that -- below the cutoff amount set as the lower limit AND not able to detect any virusus (?virii?).
SVR is what happens when one has been 'Undetected' for 12 weeks AFTER treatment is finished, or 24 weeks, if that is the protocol for the med combination one is treated with. That then becomes SVR12 or SVR24.
Example, many on here have been Undetected since Week 4 of treatment. Some of us were measured as <12IU/ml Detected at 3 or 4 weeks but did not attain <12IU/ml until weeks 7 or 8.
I used <12 in the example as the test I was given used that. Some use the <20 mentioned above and some, maybe last year?, used <42.
Hope this helps.
I don't think you can claim totally undetected till you have obtained SVR.
I remember a statement on all my tests during treatment about being "detected".......even when I was undetected. It was very confusing.
yes
That was the exact wording, Pooh. Although the VL results come to me as a message from my doc. Because, even though I have access to all the other lab results, the VL is "top secret"
I guess I could ask for a printout of the test. I reviewed last year's results when I was treating with S/O
The tests said:
HCV VIRAL LOAD NOT DETECTED
So, that is why I was confused
But I think I am not going to stress about it. My labs look great and I have less than a month of treatment to go
Plus, my undetected status from previous treatment didn't last long in the real world. Back to a mil 4 weeks EOT
This is an exciting time for those who relapsed on prior non-interferon treatments as our results are just beginning to come in
Good luck to everyone in that boat that this is our time to beat this f****** virus
My viral load came back as .....
"less than 20 IU/mL of Hepatitis C virus detected "
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Was that the exact wording?
Depending on the exact wording, that result usually means that the virus was detected but the amount of virus was under the limit of quantification (cannot be counted).
Detected does not mean Undetected. Detected means Detected.
It means the virus can still be seen (detected) but in such a small amount it cannot be counted (quantified). Bet the next test will be totally undetected.
OK then
Thank you 2!!!!
only 27 days left of treatment and then I'm on to the waiting game
But at least I can break up with Riba. I gave him a shot but I really feel that we don't have that much in common and he turned out to be very self-centered
Means the tested HCV is below the limit of detection. The limit being 20IU/mL. Congratulations!
In my book UND means UND.
Congragulations my friend!
You may want to stop 2nd guessing your Hep C status.
Looks like smooth sailing and the journey is almost over.
.....Kim
Or, perhaps the answer is more nuanced and depends on the type of VL test used?
LLOQ = "Lower Limit Of Quantification"
LLOD = "Lower Limit Of Detection"