The last time I treated I remember the chart that has my shot dates suggested I take two 500 mg Tylenol around the time I administer the shot. There used to be some kind of ongoing "pro/con" discussion here on the forum related to this. I notice this time around I rarely ever see Acetaminophen mentioned. Do those of you who are treating take it? What, if anything has your clinician said about it? I'm actually not even sure if it is part of the SOC (then or now). I haven't kept up with all the nuances of treatment over the years♫